Enantioselective synthesis of chiral α,α-dialkyl indoles and related azoles by cobalt-catalyzed hydroalkylation and regioselectivity switch
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DOI: 10.1038/s41467-024-48175-7
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- Lun Li & Jiangtao Ren & Jingjie Zhou & Xiaomei Wu & Zhihui Shao & Xiaodong Yang & Deyun Qian, 2022. "Enantioselective synthesis of N-alkylindoles enabled by nickel-catalyzed C-C coupling," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Michael T. McCabe & Heidi M. Ott & Gopinath Ganji & Susan Korenchuk & Christine Thompson & Glenn S. Van Aller & Yan Liu & Alan P. Graves & Anthony Della Pietra III & Elsie Diaz & Louis V. LaFrance & M, 2012. "EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations," Nature, Nature, vol. 492(7427), pages 108-112, December.
- Lei Wang & Chuiyi Lin & Qinglei Chong & Zhihan Zhang & Fanke Meng, 2023. "Photoredox cobalt-catalyzed regio-, diastereo- and enantioselective propargylation of aldehydes via propargyl radicals," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Jia-Wang Wang & Yan Li & Wan Nie & Zhe Chang & Zi-An Yu & Yi-Fan Zhao & Xi Lu & Yao Fu, 2021. "Catalytic asymmetric reductive hydroalkylation of enamides and enecarbamates to chiral aliphatic amines," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
- Kun Xu & Thomas Gilles & Bernhard Breit, 2015. "Asymmetric synthesis of N-allylic indoles via regio- and enantioselective allylation of aryl hydrazines," Nature Communications, Nature, vol. 6(1), pages 1-7, November.
- Yingcheng Wang & Sheng Wang & Wenyu Shan & Zhihui Shao, 2020. "Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate," Nature Communications, Nature, vol. 11(1), pages 1-10, December.
- Zhaobin Wang & Haolin Yin & Gregory C. Fu, 2018. "Catalytic enantioconvergent coupling of secondary and tertiary electrophiles with olefins," Nature, Nature, vol. 563(7731), pages 379-383, November.
- Shan Wang & Jian-Xin Zhang & Tian-Yi Zhang & Huan Meng & Bi-Hong Chen & Wei Shu, 2021. "Enantioselective access to chiral aliphatic amines and alcohols via Ni-catalyzed hydroalkylations," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
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