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Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence

Author

Listed:
  • Bao Feng

    (Jiangmen Central Hospital
    Guilin University of Aerospace Technology)

  • Jiangfeng Shi

    (Guilin University of Aerospace Technology
    Guilin University of Electronic Technology)

  • Liebin Huang

    (Jiangmen Central Hospital)

  • Zhiqi Yang

    (Meizhou People’s Hospital)

  • Shi-Ting Feng

    (The First Affiliated Hospital of Sun Yat-sen University)

  • Jianpeng Li

    (Dongguan People’s Hospital)

  • Qinxian Chen

    (Jiangmen Central Hospital)

  • Huimin Xue

    (Jiangmen Central Hospital)

  • Xiangguang Chen

    (Meizhou People’s Hospital)

  • Cuixia Wan

    (Meizhou People’s Hospital)

  • Qinghui Hu

    (Guilin University of Aerospace Technology)

  • Enming Cui

    (Jiangmen Central Hospital)

  • Yehang Chen

    (Guilin University of Aerospace Technology)

  • Wansheng Long

    (Jiangmen Central Hospital)

Abstract

The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles related to privacy protection. Therefore, the present study aims to establish a robust federated learning model to overcome the data island problem and identify high-risk patients with postoperative gastric cancer recurrence in a multicentre, cross-institution setting, thereby enabling robust treatment with significant value. In the present study, we collect data from four independent medical institutions for experimentation. The robust federated learning model algorithm yields area under the receiver operating characteristic curve (AUC) values of 0.710, 0.798, 0.809, and 0.869 across four data centres. Additionally, the effectiveness of the algorithm is evaluated, and both adaptive and common features are identified through analysis.

Suggested Citation

  • Bao Feng & Jiangfeng Shi & Liebin Huang & Zhiqi Yang & Shi-Ting Feng & Jianpeng Li & Qinxian Chen & Huimin Xue & Xiangguang Chen & Cuixia Wan & Qinghui Hu & Enming Cui & Yehang Chen & Wansheng Long, 2024. "Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-44946-4
    DOI: 10.1038/s41467-024-44946-4
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    References listed on IDEAS

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    1. Benoît Schmauch & Alberto Romagnoni & Elodie Pronier & Charlie Saillard & Pascale Maillé & Julien Calderaro & Aurélie Kamoun & Meriem Sefta & Sylvain Toldo & Mikhail Zaslavskiy & Thomas Clozel & Matah, 2020. "A deep learning model to predict RNA-Seq expression of tumours from whole slide images," Nature Communications, Nature, vol. 11(1), pages 1-15, December.
    2. Dexin Chen & Meiting Fu & Liangjie Chi & Liyan Lin & Jiaxin Cheng & Weisong Xue & Chenyan Long & Wei Jiang & Xiaoyu Dong & Jian Sui & Dajia Lin & Jianping Lu & Shuangmu Zhuo & Side Liu & Guoxin Li & G, 2022. "Prognostic and predictive value of a pathomics signature in gastric cancer," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
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    1. Edward H. Lee & Michelle Han & Jason Wright & Michael Kuwabara & Jacob Mevorach & Gang Fu & Olivia Choudhury & Ujjwal Ratan & Michael Zhang & Matthias W. Wagner & Robert Goetti & Sebastian Toescu & Se, 2024. "An international study presenting a federated learning AI platform for pediatric brain tumors," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

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