IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v15y2024i1d10.1038_s41467-024-44946-4.html
   My bibliography  Save this article

Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence

Author

Listed:
  • Bao Feng

    (Jiangmen Central Hospital
    Guilin University of Aerospace Technology)

  • Jiangfeng Shi

    (Guilin University of Aerospace Technology
    Guilin University of Electronic Technology)

  • Liebin Huang

    (Jiangmen Central Hospital)

  • Zhiqi Yang

    (Meizhou People’s Hospital)

  • Shi-Ting Feng

    (The First Affiliated Hospital of Sun Yat-sen University)

  • Jianpeng Li

    (Dongguan People’s Hospital)

  • Qinxian Chen

    (Jiangmen Central Hospital)

  • Huimin Xue

    (Jiangmen Central Hospital)

  • Xiangguang Chen

    (Meizhou People’s Hospital)

  • Cuixia Wan

    (Meizhou People’s Hospital)

  • Qinghui Hu

    (Guilin University of Aerospace Technology)

  • Enming Cui

    (Jiangmen Central Hospital)

  • Yehang Chen

    (Guilin University of Aerospace Technology)

  • Wansheng Long

    (Jiangmen Central Hospital)

Abstract

The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles related to privacy protection. Therefore, the present study aims to establish a robust federated learning model to overcome the data island problem and identify high-risk patients with postoperative gastric cancer recurrence in a multicentre, cross-institution setting, thereby enabling robust treatment with significant value. In the present study, we collect data from four independent medical institutions for experimentation. The robust federated learning model algorithm yields area under the receiver operating characteristic curve (AUC) values of 0.710, 0.798, 0.809, and 0.869 across four data centres. Additionally, the effectiveness of the algorithm is evaluated, and both adaptive and common features are identified through analysis.

Suggested Citation

  • Bao Feng & Jiangfeng Shi & Liebin Huang & Zhiqi Yang & Shi-Ting Feng & Jianpeng Li & Qinxian Chen & Huimin Xue & Xiangguang Chen & Cuixia Wan & Qinghui Hu & Enming Cui & Yehang Chen & Wansheng Long, 2024. "Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-44946-4
    DOI: 10.1038/s41467-024-44946-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-024-44946-4
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/s41467-024-44946-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Benoît Schmauch & Alberto Romagnoni & Elodie Pronier & Charlie Saillard & Pascale Maillé & Julien Calderaro & Aurélie Kamoun & Meriem Sefta & Sylvain Toldo & Mikhail Zaslavskiy & Thomas Clozel & Matah, 2020. "A deep learning model to predict RNA-Seq expression of tumours from whole slide images," Nature Communications, Nature, vol. 11(1), pages 1-15, December.
    2. Dexin Chen & Meiting Fu & Liangjie Chi & Liyan Lin & Jiaxin Cheng & Weisong Xue & Chenyan Long & Wei Jiang & Xiaoyu Dong & Jian Sui & Dajia Lin & Jianping Lu & Shuangmu Zhuo & Side Liu & Guoxin Li & G, 2022. "Prognostic and predictive value of a pathomics signature in gastric cancer," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Yangzi Chen & Bohong Wang & Yizi Zhao & Xinxin Shao & Mingshuo Wang & Fuhai Ma & Laishou Yang & Meng Nie & Peng Jin & Ke Yao & Haibin Song & Shenghan Lou & Hang Wang & Tianshu Yang & Yantao Tian & Pen, 2024. "Metabolomic machine learning predictor for diagnosis and prognosis of gastric cancer," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    2. Omar S. M. El Nahhas & Chiara M. L. Loeffler & Zunamys I. Carrero & Marko Treeck & Fiona R. Kolbinger & Katherine J. Hewitt & Hannah S. Muti & Mara Graziani & Qinghe Zeng & Julien Calderaro & Nadina O, 2024. "Regression-based Deep-Learning predicts molecular biomarkers from pathology slides," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    3. Duy Pham & Xiao Tan & Brad Balderson & Jun Xu & Laura F. Grice & Sohye Yoon & Emily F. Willis & Minh Tran & Pui Yeng Lam & Arti Raghubar & Priyakshi Kalita-de Croft & Sunil Lakhani & Jana Vukovic & Ma, 2023. "Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues," Nature Communications, Nature, vol. 14(1), pages 1-25, December.
    4. Weiwei Wang & Yuanshen Zhao & Lianghong Teng & Jing Yan & Yang Guo & Yuning Qiu & Yuchen Ji & Bin Yu & Dongling Pei & Wenchao Duan & Minkai Wang & Li Wang & Jingxian Duan & Qiuchang Sun & Shengnan Wan, 2023. "Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    5. Petr Holub & Heimo Müller & Tomáš Bíl & Luca Pireddu & Markus Plass & Fabian Prasser & Irene Schlünder & Kurt Zatloukal & Rudolf Nenutil & Tomáš Brázdil, 2023. "Privacy risks of whole-slide image sharing in digital pathology," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    6. Yuanning Zheng & Francisco Carrillo-Perez & Marija Pizurica & Dieter Henrik Heiland & Olivier Gevaert, 2023. "Spatial cellular architecture predicts prognosis in glioblastoma," Nature Communications, Nature, vol. 14(1), pages 1-16, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-44946-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.