Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors
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DOI: 10.1038/s41467-023-44637-6
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- Per Plenge & Dongxue Yang & Kristine Salomon & Louise Laursen & Iris E. Kalenderoglou & Amy H. Newman & Eric Gouaux & Jonathan A. Coleman & Claus J. Loland, 2021. "The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
- Kevin H. Wang & Aravind Penmatsa & Eric Gouaux, 2015. "Neurotransmitter and psychostimulant recognition by the dopamine transporter," Nature, Nature, vol. 521(7552), pages 322-327, May.
- Jonathan A. Coleman & Evan M. Green & Eric Gouaux, 2016. "X-ray structures and mechanism of the human serotonin transporter," Nature, Nature, vol. 532(7599), pages 334-339, April.
- Jonathan A. Coleman & Dongxue Yang & Zhiyu Zhao & Po-Chao Wen & Craig Yoshioka & Emad Tajkhorshid & Eric Gouaux, 2019. "Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport," Nature, Nature, vol. 569(7754), pages 141-145, May.
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