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Thin, soft, wearable system for continuous wireless monitoring of artery blood pressure

Author

Listed:
  • Jian Li

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Huiling Jia

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Jingkun Zhou

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Xingcan Huang

    (City University of Hong Kong)

  • Long Xu

    (Jilin University)

  • Shengxin Jia

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Zhan Gao

    (City University of Hong Kong)

  • Kuanming Yao

    (City University of Hong Kong)

  • Dengfeng Li

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Binbin Zhang

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Yiming Liu

    (City University of Hong Kong)

  • Ya Huang

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Yue Hu

    (City University of Hong Kong)

  • Guangyao Zhao

    (City University of Hong Kong)

  • Zitong Xu

    (City University of Hong Kong)

  • Jiyu Li

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Chun Ki Yiu

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Yuyu Gao

    (City University of Hong Kong)

  • Mengge Wu

    (City University of Hong Kong
    University of Electronic Science and Technology of China (UESTC))

  • Yanli Jiao

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Qiang Zhang

    (City University of Hong Kong)

  • Xuecheng Tai

    (Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE)
    Hong Kong Baptist University)

  • Raymond H. Chan

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Yuanting Zhang

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE))

  • Xiaohui Ma

    (The first medical center of Chinese PLA General Hospital)

  • Xinge Yu

    (City University of Hong Kong
    Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE)
    City University of Hong Kong Shenzhen Research Institute)

Abstract

Continuous monitoring of arterial blood pressure (BP) outside of a clinical setting is crucial for preventing and diagnosing hypertension related diseases. However, current continuous BP monitoring instruments suffer from either bulky systems or poor user-device interfacial performance, hampering their applications in continuous BP monitoring. Here, we report a thin, soft, miniaturized system (TSMS) that combines a conformal piezoelectric sensor array, an active pressure adaptation unit, a signal processing module, and an advanced machine learning method, to allow real wearable, continuous wireless monitoring of ambulatory artery BP. By optimizing the materials selection, control/sampling strategy, and system integration, the TSMS exhibits improved interfacial performance while maintaining Grade A level measurement accuracy. Initial trials on 87 volunteers and clinical tracking of two hypertension individuals prove the capability of the TSMS as a reliable BP measurement product, and its feasibility and practical usability in precise BP control and personalized diagnosis schemes development.

Suggested Citation

  • Jian Li & Huiling Jia & Jingkun Zhou & Xingcan Huang & Long Xu & Shengxin Jia & Zhan Gao & Kuanming Yao & Dengfeng Li & Binbin Zhang & Yiming Liu & Ya Huang & Yue Hu & Guangyao Zhao & Zitong Xu & Jiyu, 2023. "Thin, soft, wearable system for continuous wireless monitoring of artery blood pressure," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
  • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-40763-3
    DOI: 10.1038/s41467-023-40763-3
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    References listed on IDEAS

    as
    1. Xinge Yu & Zhaoqian Xie & Yang Yu & Jungyup Lee & Abraham Vazquez-Guardado & Haiwen Luan & Jasper Ruban & Xin Ning & Aadeel Akhtar & Dengfeng Li & Bowen Ji & Yiming Liu & Rujie Sun & Jingyue Cao & Qin, 2019. "Skin-integrated wireless haptic interfaces for virtual and augmented reality," Nature, Nature, vol. 575(7783), pages 473-479, November.
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    Cited by:

    1. Jian Li & Shengxin Jia & Dengfeng Li & Lung Chow & Qiang Zhang & Yiyuan Yang & Xiao Bai & Qingao Qu & Yuyu Gao & Zhiyuan Li & Zongze Li & Rui Shi & Binbin Zhang & Ya Huang & Xinyu Pan & Yue Hu & Zhan , 2024. "Wearable bio-adhesive metal detector array (BioMDA) for spinal implants," Nature Communications, Nature, vol. 15(1), pages 1-12, December.

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