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Chromosome-level genome assembly and population genomic resource to accelerate orphan crop lablab breeding

Author

Listed:
  • Isaac Njaci

    (International Livestock Research Institute
    John Innes Centre, Norwich Research Park)

  • Bernice Waweru

    (International Livestock Research Institute)

  • Nadia Kamal

    (Helmholtz Zentrum München, Plant Genome and Systems Biology)

  • Meki Shehabu Muktar

    (International Livestock Research Institute)

  • David Fisher

    (University of Southampton, School of Biological Sciences)

  • Heidrun Gundlach

    (Helmholtz Zentrum München, Plant Genome and Systems Biology)

  • Collins Muli

    (International Livestock Research Institute)

  • Lucy Muthui

    (International Livestock Research Institute)

  • Mary Maranga

    (Jomo Kenyatta University of Agriculture and Technology)

  • Davies Kiambi

    (Pwani University)

  • Brigitte L. Maass

    (Georg-August-University Göttingen)

  • Peter M. F. Emmrich

    (John Innes Centre, Norwich Research Park
    University of East Anglia)

  • Jean-Baka Domelevo Entfellner

    (International Livestock Research Institute)

  • Manuel Spannagl

    (Helmholtz Zentrum München, Plant Genome and Systems Biology)

  • Mark A. Chapman

    (University of Southampton, School of Biological Sciences)

  • Oluwaseyi Shorinola

    (International Livestock Research Institute
    John Innes Centre, Norwich Research Park)

  • Chris S. Jones

    (International Livestock Research Institute)

Abstract

Under-utilised orphan crops hold the key to diversified and climate-resilient food systems. Here, we report on orphan crop genomics using the case of Lablab purpureus (L.) Sweet (lablab) - a legume native to Africa and cultivated throughout the tropics for food and forage. Our Africa-led plant genome collaboration produces a high-quality chromosome-scale assembly of the lablab genome. Our assembly highlights the genome organisation of the trypsin inhibitor genes - an important anti-nutritional factor in lablab. We also re-sequence cultivated and wild lablab accessions from Africa confirming two domestication events. Finally, we examine the genetic and phenotypic diversity in a comprehensive lablab germplasm collection and identify genomic loci underlying variation of important agronomic traits in lablab. The genomic data generated here provide a valuable resource for lablab improvement. Our inclusive collaborative approach also presents an example that can be explored by other researchers sequencing indigenous crops, particularly from low and middle-income countries (LMIC).

Suggested Citation

  • Isaac Njaci & Bernice Waweru & Nadia Kamal & Meki Shehabu Muktar & David Fisher & Heidrun Gundlach & Collins Muli & Lucy Muthui & Mary Maranga & Davies Kiambi & Brigitte L. Maass & Peter M. F. Emmrich, 2023. "Chromosome-level genome assembly and population genomic resource to accelerate orphan crop lablab breeding," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
  • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-37489-7
    DOI: 10.1038/s41467-023-37489-7
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    References listed on IDEAS

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