Location bias contributes to functionally selective responses of biased CXCR3 agonists
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DOI: 10.1038/s41467-022-33569-2
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- Naomi R. Latorraca & Jason K. Wang & Brian Bauer & Raphael J. L. Townshend & Scott A. Hollingsworth & Julia E. Olivieri & H. Eric Xu & Martha E. Sommer & Ron O. Dror, 2018. "Molecular mechanism of GPCR-mediated arrestin activation," Nature, Nature, vol. 557(7705), pages 452-456, May.
- Manuel Grundmann & Nicole Merten & Davide Malfacini & Asuka Inoue & Philip Preis & Katharina Simon & Nelly Rüttiger & Nicole Ziegler & Tobias Benkel & Nina Katharina Schmitt & Satoru Ishida & Ines Mül, 2018. "Lack of beta-arrestin signaling in the absence of active G proteins," Nature Communications, Nature, vol. 9(1), pages 1-16, December.
- Punita Kumari & Ashish Srivastava & Ramanuj Banerjee & Eshan Ghosh & Pragya Gupta & Ravi Ranjan & Xin Chen & Bhagyashri Gupta & Charu Gupta & Deepika Jaiman & Arun K. Shukla, 2016. "Functional competence of a partially engaged GPCR–β-arrestin complex," Nature Communications, Nature, vol. 7(1), pages 1-16, December.
- Roshanak Irannejad & Jin C. Tomshine & Jon R. Tomshine & Michael Chevalier & Jacob P. Mahoney & Jan Steyaert & Søren G. F. Rasmussen & Roger K. Sunahara & Hana El-Samad & Bo Huang & Mark von Zastrow, 2013. "Conformational biosensors reveal GPCR signalling from endosomes," Nature, Nature, vol. 495(7442), pages 534-538, March.
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- Shane C. Wright & Aikaterini Motso & Stefania Koutsilieri & Christian M. Beusch & Pierre Sabatier & Alessandro Berghella & Élodie Blondel-Tepaz & Kimberley Mangenot & Ioannis Pittarokoilis & Despoina-, 2023. "GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
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