ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer
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DOI: 10.1038/s41467-022-33172-5
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- Beth O. Van Emburgh & Sabrina Arena & Giulia Siravegna & Luca Lazzari & Giovanni Crisafulli & Giorgio Corti & Benedetta Mussolin & Federica Baldi & Michela Buscarino & Alice Bartolini & Emanuele Valto, 2016. "Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer," Nature Communications, Nature, vol. 7(1), pages 1-9, December.
- Andrea Bertotti & Eniko Papp & Siân Jones & Vilmos Adleff & Valsamo Anagnostou & Barbara Lupo & Mark Sausen & Jillian Phallen & Carolyn A. Hruban & Collin Tokheim & Noushin Niknafs & Monica Nesselbush, 2015. "The genomic landscape of response to EGFR blockade in colorectal cancer," Nature, Nature, vol. 526(7572), pages 263-267, October.
- Sanjeev Mariathasan & Shannon J. Turley & Dorothee Nickles & Alessandra Castiglioni & Kobe Yuen & Yulei Wang & Edward E. Kadel III & Hartmut Koeppen & Jillian L. Astarita & Rafael Cubas & Suchit Jhunj, 2018. "TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells," Nature, Nature, vol. 554(7693), pages 544-548, February.
- Sandra Misale & Rona Yaeger & Sebastijan Hobor & Elisa Scala & Manickam Janakiraman & David Liska & Emanuele Valtorta & Roberta Schiavo & Michela Buscarino & Giulia Siravegna & Katia Bencardino & Andr, 2012. "Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer," Nature, Nature, vol. 486(7404), pages 532-536, June.
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