IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern
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DOI: 10.1038/s41467-022-33030-4
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- Kenneth H. Dinnon & Sarah R. Leist & Alexandra Schäfer & Caitlin E. Edwards & David R. Martinez & Stephanie A. Montgomery & Ande West & Boyd L. Yount & Yixuan J. Hou & Lily E. Adams & Kendra L. Gully , 2020. "A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures," Nature, Nature, vol. 586(7830), pages 560-566, October.
- M. Alejandra Tortorici & Nadine Czudnochowski & Tyler N. Starr & Roberta Marzi & Alexandra C. Walls & Fabrizia Zatta & John E. Bowen & Stefano Jaconi & Julia Iulio & Zhaoqian Wang & Anna Marco & Saman, 2021. "Broad sarbecovirus neutralization by a human monoclonal antibody," Nature, Nature, vol. 597(7874), pages 103-108, September.
- Delphine Planas & David Veyer & Artem Baidaliuk & Isabelle Staropoli & Florence Guivel-Benhassine & Maaran Michael Rajah & Cyril Planchais & Françoise Porrot & Nicolas Robillard & Julien Puech & Matth, 2021. "Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization," Nature, Nature, vol. 596(7871), pages 276-280, August.
- Seiya Ozono & Yanzhao Zhang & Hirotaka Ode & Kaori Sano & Toong Seng Tan & Kazuo Imai & Kazuyasu Miyoshi & Satoshi Kishigami & Takamasa Ueno & Yasumasa Iwatani & Tadaki Suzuki & Kenzo Tokunaga, 2021. "SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
- Pengfei Wang & Manoj S. Nair & Lihong Liu & Sho Iketani & Yang Luo & Yicheng Guo & Maple Wang & Jian Yu & Baoshan Zhang & Peter D. Kwong & Barney S. Graham & John R. Mascola & Jennifer Y. Chang & Mich, 2021. "Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7," Nature, Nature, vol. 593(7857), pages 130-135, May.
- Sin Fun Sia & Li-Meng Yan & Alex W. H. Chin & Kevin Fung & Ka-Tim Choy & Alvina Y. L. Wong & Prathanporn Kaewpreedee & Ranawaka A. P. M. Perera & Leo L. M. Poon & John M. Nicholls & Malik Peiris & Hui, 2020. "Pathogenesis and transmission of SARS-CoV-2 in golden hamsters," Nature, Nature, vol. 583(7818), pages 834-838, July.
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