High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer
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DOI: 10.1038/s41467-022-32828-6
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- Peter Priestley & Jonathan Baber & Martijn P. Lolkema & Neeltje Steeghs & Ewart Bruijn & Charles Shale & Korneel Duyvesteyn & Susan Haidari & Arne Hoeck & Wendy Onstenk & Paul Roepman & Mircea Voda & , 2019. "Pan-cancer whole-genome analyses of metastatic solid tumours," Nature, Nature, vol. 575(7781), pages 210-216, November.
- Luigi Formisano & Yao Lu & Alberto Servetto & Ariella B. Hanker & Valerie M. Jansen & Joshua A. Bauer & Dhivya R. Sudhan & Angel L. Guerrero-Zotano & Sarah Croessmann & Yan Guo & Paula Gonzalez Ericss, 2019. "Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Yingdai Gao & Peng Yang & Hongmei Shen & Hui Yu & Xianmin Song & Liyan Zhang & Peng Zhang & Haizi Cheng & Zhaojun Xie & Sha Hao & Fang Dong & Shihui Ma & Qing Ji & Patrick Bartlow & Yahui Ding & Liron, 2015. "Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo expansion of haematopoietic stem cells," Nature Communications, Nature, vol. 6(1), pages 1-10, May.
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- M. T. Herrera-Abreu & J. Guan & U. Khalid & J. Ning & M. R. Costa & J. Chan & Q. Li & J-P. Fortin & W. R. Wong & P. Perampalam & A. Biton & W. Sandoval & J. Vijay & M. Hafner & R. Cutts & G. Wilson & , 2024. "Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancer," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
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