High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-022-32828-6
Download full text from publisher
References listed on IDEAS
- Luigi Formisano & Yao Lu & Alberto Servetto & Ariella B. Hanker & Valerie M. Jansen & Joshua A. Bauer & Dhivya R. Sudhan & Angel L. Guerrero-Zotano & Sarah Croessmann & Yan Guo & Paula Gonzalez Ericss, 2019. "Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Yingdai Gao & Peng Yang & Hongmei Shen & Hui Yu & Xianmin Song & Liyan Zhang & Peng Zhang & Haizi Cheng & Zhaojun Xie & Sha Hao & Fang Dong & Shihui Ma & Qing Ji & Patrick Bartlow & Yahui Ding & Liron, 2015. "Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo expansion of haematopoietic stem cells," Nature Communications, Nature, vol. 6(1), pages 1-10, May.
- Peter Priestley & Jonathan Baber & Martijn P. Lolkema & Neeltje Steeghs & Ewart Bruijn & Charles Shale & Korneel Duyvesteyn & Susan Haidari & Arne Hoeck & Wendy Onstenk & Paul Roepman & Mircea Voda & , 2019. "Pan-cancer whole-genome analyses of metastatic solid tumours," Nature, Nature, vol. 575(7781), pages 210-216, November.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Cambrosio, Alberto & Campbell, Jonah & Keating, Peter & Polk, Jessica B. & Aguilar-Mahecha, Adriana & Basik, Mark, 2022. "Healthcare policy by other means: Cancer clinical research as “oncopolicy”," Social Science & Medicine, Elsevier, vol. 292(C).
- Oriol Pich & Iker Reyes-Salazar & Abel Gonzalez-Perez & Nuria Lopez-Bigas, 2022. "Discovering the drivers of clonal hematopoiesis," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Eline J. M. Bertrums & Jurrian K. Kanter & Lucca L. M. Derks & Mark Verheul & Laurianne Trabut & Markus J. Roosmalen & Henrik Hasle & Evangelia Antoniou & Dirk Reinhardt & Michael N. Dworzak & Nora Mü, 2024. "Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
- Roberta Esposito & Andrés Lanzós & Tina Uroda & Sunandini Ramnarayanan & Isabel Büchi & Taisia Polidori & Hugo Guillen-Ramirez & Ante Mihaljevic & Bernard Mefi Merlin & Lia Mela & Eugenio Zoni & Lusin, 2023. "Tumour mutations in long noncoding RNAs enhance cell fitness," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
- Erik Elias & Arman Ardalan & Markus Lindberg & Susanne E. Reinsbach & Andreas Muth & Ola Nilsson & Yvonne Arvidsson & Erik Larsson, 2021. "Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine," Nature Communications, Nature, vol. 12(1), pages 1-8, December.
- Luan Nguyen & Arne Hoeck & Edwin Cuppen, 2022. "Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Ozvan Bocher & Cristen J. Willer & Eleftheria Zeggini, 2023. "Unravelling the genetic architecture of human complex traits through whole genome sequencing," Nature Communications, Nature, vol. 14(1), pages 1-4, December.
- Zhe Jiang & YoungJun Ju & Amjad Ali & Philip E. D. Chung & Patryk Skowron & Dong-Yu Wang & Mariusz Shrestha & Huiqin Li & Jeff C. Liu & Ioulia Vorobieva & Ronak Ghanbari-Azarnier & Ethel Mwewa & Maria, 2023. "Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-22, December.
- Zhu, Guang & Lin, Zhenhua, 2021. "Commentary on statistical mechanical models of cancer," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 572(C).
- Mischan Vali-Pour & Solip Park & Jose Espinosa-Carrasco & Daniel Ortiz-Martínez & Ben Lehner & Fran Supek, 2022. "The impact of rare germline variants on human somatic mutation processes," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
- Yi Zhang & Shuyan Zhou & Yan Kai & Ya-qin Zhang & Changmin Peng & Zhuqing Li & Muhammad Jameel mughal & Belmar Julie & Xiaoyan Zheng & Junfeng Ma & Cynthia X. Ma & Min Shen & Matthew D. Hall & Shunqia, 2024. "O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- R. C. Coombes & P. D. Badman & J. P. Lozano-Kuehne & X. Liu & I. R. Macpherson & I. Zubairi & R. D. Baird & N. Rosenfeld & J. Garcia-Corbacho & N. Cresti & R. Plummer & A. Armstrong & R. Allerton & D., 2022. "Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
- Lino Möhrmann & Maximilian Werner & Małgorzata Oleś & Andreas Mock & Sebastian Uhrig & Arne Jahn & Simon Kreutzfeldt & Martina Fröhlich & Barbara Hutter & Nagarajan Paramasivam & Daniela Richter & Kat, 2022. "Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Maud Rijnders & J. Alberto Nakauma-González & Debbie G. J. Robbrecht & Alberto Gil-Jimenez & Hayri E. Balcioglu & Astrid A. M. Oostvogels & Maureen J. B. Aarts & Joost L. Boormans & Paul Hamberg & Mic, 2024. "Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Tas ML & Van Noesel MM & Van den Boogaard ML & Schild GG & Hehir-Kwa JY & Molenaar JJ & Van Noesel MM & Van de Sande MAJ & Van de Sande MAJ & Bovée JVMG & Flucke UE & Flucke UE & Koster J, 2020. "ZFP42: A New Tumor Predisposition Gene? Presentation of a Patient with two Neoplasms in Childhood," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 27(5), pages 21166-21172, May.
- Anouk C. Jong & Alexandra Danyi & Job Riet & Ronald Wit & Martin Sjöström & Felix Feng & Jeroen Ridder & Martijn P. Lolkema, 2023. "Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Nikki L. Burdett & Madelynne O. Willis & Ahwan Pandey & Laura Twomey & Sara Alaei & David D. L. Bowtell & Elizabeth L. Christie, 2024. "Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Xiaojing Wang & Anne-Marie Langevin & Peter J. Houghton & Siyuan Zheng, 2022. "Genomic disparities between cancers in adolescent and young adults and in older adults," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- W. Dean Pontius & Ellen S. Hong & Zachary J. Faber & Jeremy Gray & Craig D. Peacock & Ian Bayles & Katreya Lovrenert & Diana H. Chin & Berkley E. Gryder & Cynthia F. Bartels & Peter C. Scacheri, 2023. "Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Jorge Gómez Tejeda Zañudo & Romualdo Barroso-Sousa & Esha Jain & Qingchun Jin & Tianyu Li & Jorge E. Buendia-Buendia & Alyssa Pereslete & Daniel L. Abravanel & Arlindo R. Ferreira & Eileen Wrabel & Ka, 2024. "Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-32828-6. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.