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A multi-product multi-period stochastic model for a blood supply chain considering blood substitution and demand uncertainty

Author

Listed:
  • Yuan Xu

    (Dalian Maritime University)

  • Joseph Szmerekovsky

    (College of Business, North Dakota State University)

Abstract

This paper presents a multi-product multi-period stochastic program for an integrated blood supply chain that considers red blood cells and platelets while accounting for multi-product interactions, demand uncertainty, blood age information, blood type substitution, and three types of patients. The aim is to minimize the total cost incurred during the collection, production, inventory, and distribution echelons under centralized control. The supply chains for red blood cells and platelets intertwine at the collection and production echelons as collected whole blood can be separated into red blood cells and platelets at the same time. By adapting to a real-world blood supply chain with one blood center, three collection facilities, and five hospitals, we found a cost advantage of the multi-product model over an uncoordinated model where the red blood cell and platelet supply chains are considered separately. Further sensitivity analyses indicated that the cost savings of the multi-product model mainly come from variations in the number of whole blood donors. These findings suggest that healthcare managers are able to see tremendous improvement in cost efficiency by considering red blood cell and platelet supply chains as a whole, especially with more whole blood donations and a higher percentage of whole blood derived platelets pooled for transfusion.

Suggested Citation

  • Yuan Xu & Joseph Szmerekovsky, 2022. "A multi-product multi-period stochastic model for a blood supply chain considering blood substitution and demand uncertainty," Health Care Management Science, Springer, vol. 25(3), pages 441-459, September.
    • Handle: RePEc:kap:hcarem:v:25:y:2022:i:3:d:10.1007_s10729-022-09593-5
    DOI: 10.1007/s10729-022-09593-5
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    References listed on IDEAS

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    1. Civelek, Ismail & Karaesmen, Itir & Scheller-Wolf, Alan, 2015. "Blood platelet inventory management with protection levels," European Journal of Operational Research, Elsevier, vol. 243(3), pages 826-838.
    2. Fahimnia, Behnam & Jabbarzadeh, Armin & Ghavamifar, Ali & Bell, Michael, 2017. "Supply chain design for efficient and effective blood supply in disasters," International Journal of Production Economics, Elsevier, vol. 183(PC), pages 700-709.
    3. Andres F. Osorio & Sally C. Brailsford & Honora K. Smith, 2015. "A structured review of quantitative models in the blood supply chain: a taxonomic framework for decision-making," International Journal of Production Research, Taylor & Francis Journals, vol. 53(24), pages 7191-7212, December.
    4. Wang, Ke-Ming & Ma, Zu-Jun, 2015. "Age-based policy for blood transshipment during blood shortage," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 80(C), pages 166-183.
    5. Dillon, Mary & Oliveira, Fabricio & Abbasi, Babak, 2017. "A two-stage stochastic programming model for inventory management in the blood supply chain," International Journal of Production Economics, Elsevier, vol. 187(C), pages 27-41.
    6. Ensafian, Hamidreza & Yaghoubi, Saeed, 2017. "Robust optimization model for integrated procurement, production and distribution in platelet supply chain," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 103(C), pages 32-55.
    7. Bryan L. Deuermeyer & William P. Pierskalla, 1978. "A By-Product Production System with an Alternative," Management Science, INFORMS, vol. 24(13), pages 1373-1383, September.
    8. Mirzapour Al-e-hashem, S.M.J. & Malekly, H. & Aryanezhad, M.B., 2011. "A multi-objective robust optimization model for multi-product multi-site aggregate production planning in a supply chain under uncertainty," International Journal of Production Economics, Elsevier, vol. 134(1), pages 28-42, November.
    9. Behzad Zahiri & Mir Saman Pishvaee, 2017. "Blood supply chain network design considering blood group compatibility under uncertainty," International Journal of Production Research, Taylor & Francis Journals, vol. 55(7), pages 2013-2033, April.
    10. Duan, Qinglin & Liao, T. Warren, 2013. "A new age-based replenishment policy for supply chain inventory optimization of highly perishable products," International Journal of Production Economics, Elsevier, vol. 145(2), pages 658-671.
    11. Duan, Qinglin & Liao, T. Warren, 2014. "Optimization of blood supply chain with shortened shelf lives and ABO compatibility," International Journal of Production Economics, Elsevier, vol. 153(C), pages 113-129.
    12. Beliën, Jeroen & Forcé, Hein, 2012. "Supply chain management of blood products: A literature review," European Journal of Operational Research, Elsevier, vol. 217(1), pages 1-16.
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