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Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis

Author

Listed:
  • Rowan Terrell

    (School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1S 5B6, Canada)

  • Abdallah Alami

    (School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1S 5B6, Canada)

  • Daniel Krewski

    (School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1S 5B6, Canada
    Risk Sciences International, Ottawa, ON K1P 5J6, Canada)

Abstract

Vaccines effectively protect against COVID-19, but vaccine hesitancy and refusal hinder vaccination rates. This systematic review aimed to (1) review and describe current interventions for addressing COVID-19 vaccine hesitancy/refusal and (2) assess whether these interventions are effective for increasing vaccine uptake. The protocol was registered prospectively on PROSPERO and comprehensive search included Medline, Embase, CINAHL, PsycInfo, and Web of Science databases. Only studies that evaluated the effectiveness of non-financial interventions to address COVID-19 vaccine hesitancy were included, while those focusing intentions or financial incentive were excluded. Risk of bias for all included studies was evaluated using Cochrane risk of bias tools. In total, six articles were included in the review (total participants n = 200,720). A narrative synthesis was performed due to the absence of common quantitative metrics. Except for one randomized controlled trial, all studies reported that interventions were effective, increasing COVID-19 vaccination rates. However, non-randomized studies were subject to confounding biases. Evidence on the effectiveness of COVID-19 vaccine hesitancy interventions remains limited and further evidence is needed for the development of clear guidance on effective interventions to increase vaccine uptake.

Suggested Citation

  • Rowan Terrell & Abdallah Alami & Daniel Krewski, 2023. "Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis," IJERPH, MDPI, vol. 20(12), pages 1-17, June.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:12:p:6082-:d:1166358
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    References listed on IDEAS

    as
    1. Barber, Andrew & West, Jeremy, 2022. "Conditional cash lotteries increase COVID-19 vaccination rates," Journal of Health Economics, Elsevier, vol. 81(C).
    2. Marta Serra-Garcia & Nora Szech, 2021. "Choice Architecture and Incentives Increase COVID-19 Vaccine Intentions and Test Demand," Working Papers 2021-020, Human Capital and Economic Opportunity Working Group.
    3. Katherine L. Milkman & Mitesh S. Patel & Linnea Gandhi & Heather N. Graci & Dena M. Gromet & Hung Ho & Joseph S. Kay & Timothy W. Lee & Modupe Akinola & John Beshears & Jonathan E. Bogard & Alison But, 2021. "A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment," Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, vol. 118(20), pages 2101165118-, May.
    4. Holly O. Witteman & Selma Chipenda Dansokho & Nicole Exe & Audrey Dupuis & Thierry Provencher & Brian J. Zikmund‐Fisher, 2015. "Risk Communication, Values Clarification, and Vaccination Decisions," Risk Analysis, John Wiley & Sons, vol. 35(10), pages 1801-1819, October.
    5. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    6. Hengchen Dai & Silvia Saccardo & Maria A. Han & Lily Roh & Naveen Raja & Sitaram Vangala & Hardikkumar Modi & Shital Pandya & Michael Sloyan & Daniel M. Croymans, 2021. "Behavioural nudges increase COVID-19 vaccinations," Nature, Nature, vol. 597(7876), pages 404-409, September.
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