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The Consumption of a Synbiotic Does Not Affect the Immune, Inflammatory, and Sympathovagal Parameters in Athletes and Sedentary Individuals: A Triple-Blinded, Randomized, Place-bo-Controlled Pilot Study

Author

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  • Carmen Daniela Quero-Calero

    (Faculty of Sport, Catholic University of Murcia, 30107 Murcia, Spain
    International Chair of Sports Medicine, Catholic University of Murcia, 30107 Murcia, Spain)

  • Oriol Abellán-Aynés

    (Faculty of Sport, Catholic University of Murcia, 30107 Murcia, Spain
    International Chair of Sports Medicine, Catholic University of Murcia, 30107 Murcia, Spain)

  • Pedro Manonelles

    (International Chair of Sports Medicine, Catholic University of Murcia, 30107 Murcia, Spain)

  • Eduardo Ortega

    (Grupo de Investigación en Inmunofisiología, Instituto Universitario de Investigación Biosanitaria de Extremadura (INUBE), University of Extremadura, 06006 Badajo, Spain)

Abstract

This investigation aimed to identify the effect of a synbiotic in athletes and sedentary people, and their potential varying responses regarding the immune system, autonomic regulation and body composition. Twenty-seven participants were involved in the protocol: 14 sedentary and 13 semi-professional soccer players. Both groups were randomly divided into an experimental and control group. A synbiotic (Gasteel Plus ® , Heel España S.A.U.) comprising a blend of probiotic strains, including Bifidobacterium lactis CBP-001010, Lactobacillus rhamnosus CNCM I-4036, and Bifidobacterium longum ES1, was administered to the experimental group, and a placebo was given to the control group for 30 days. Heart rate variability, body composition, and immune/inflammatory cytokines were determined. Statistically significant differences were observed between sedentary individuals and athletes in heart rate variability but not between the experimental and control groups. A difference between the athletic and sedentary group is observed with the influence of training on the effects of the synbiotic on the levels of fat mass and body-fold sum. No significant differences were shown in cytokines after the protocol study. No changes occur with the synbiotic treatment between the athlete and sedentary groups, while no negative effect was produced. Further research will be necessary to see chronic effects in the analyzed biomarkers.

Suggested Citation

  • Carmen Daniela Quero-Calero & Oriol Abellán-Aynés & Pedro Manonelles & Eduardo Ortega, 2022. "The Consumption of a Synbiotic Does Not Affect the Immune, Inflammatory, and Sympathovagal Parameters in Athletes and Sedentary Individuals: A Triple-Blinded, Randomized, Place-bo-Controlled Pilot Stu," IJERPH, MDPI, vol. 19(6), pages 1-14, March.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:6:p:3421-:d:770766
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    References listed on IDEAS

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    2. Abdullah Alansare & Ken Alford & Sukho Lee & Tommie Church & Hyun Chul Jung, 2018. "The Effects of High-Intensity Interval Training vs. Moderate-Intensity Continuous Training on Heart Rate Variability in Physically Inactive Adults," IJERPH, MDPI, vol. 15(7), pages 1-10, July.
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