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Risk of Mortality in Association with Pregnancy in Women Following Motor Vehicle Crashes: A Systematic Review and Meta-Analysis

Author

Listed:
  • Ya-Hui Chang

    (Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
    These authors contributed equally to this work.)

  • Ya-Yun Cheng

    (Department of Environmental and Occupational Health, National Cheng Kung University, Tainan 70101, Taiwan
    Department of Environmental Health, Harvard University T.H. Chan School of Public Health, Boston, MA 02115, USA
    These authors contributed equally to this work.)

  • Wen-Hsuan Hou

    (Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei 11031, Taiwan
    Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei 11031, Taiwan
    Department of Geriatrics and Gerontology, Taipei Medical University Hospital, Taipei 11031, Taiwan
    Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan)

  • Yu-Wen Chien

    (Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan)

  • Chiung-Hsin Chang

    (Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan)

  • Ping-Ling Chen

    (Graduate Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei 11031, Taiwan)

  • Tsung-Hsueh Lu

    (Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan)

  • Lucia Yovita Hendrati

    (Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, University of Airlangga, Surabaya 60115, Indonesia)

  • Chung-Yi Li

    (Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
    Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, University of Airlangga, Surabaya 60115, Indonesia
    Department of Public Health, College of Public Health, China Medical University, Taichung 40402, Taiwan
    Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung 41354, Taiwan)

  • Ning-Ping Foo

    (Department of Emergency Medicine, An Nan Hospital, China Medical University, Tainan 70965, Taiwan
    Graduate Institute of Medical Sciences, Chang Jung Christian University, Tainan 71101, Taiwan)

Abstract

The aim of the study was to provide a systematic review and meta-analysis of studies examining the association between mortality risk and motor vehicle crashes (MVCs) in pregnant women compared with nonpregnant women. We used relevant MeSH terms to identify epidemiological studies of mortality risk in relation to MVCs from PubMed, Embase, and MEDLINE databases. The Newcastle–Ottawa Scale (NOS) was used for quality assessment. For comparison of mortality from MVCs between pregnant and nonpregnant women, the pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random effects model. The eight studies selected met all inclusion criteria. These studies included 14,120 injured victims who were pregnant at the time of the incident and 207,935 victims who were not pregnant. Compared with nonpregnant women, pregnant women had a moderate but insignificant decrease in mortality risk (pooled OR = 0.68, 95% CI = 0.38–1.22, I 2 = 88.71%). Subgroup analysis revealed that the pooled OR significantly increased at 1.64 (95% CI = 1.16–2.33, I 2 < 0.01%) for two studies with a similar difference in the mean injury severity score (ISS) between pregnant and nonpregnant women. Future studies should further explore the risk factors associated with MVCs in pregnant women to reduce maternal mortality.

Suggested Citation

  • Ya-Hui Chang & Ya-Yun Cheng & Wen-Hsuan Hou & Yu-Wen Chien & Chiung-Hsin Chang & Ping-Ling Chen & Tsung-Hsueh Lu & Lucia Yovita Hendrati & Chung-Yi Li & Ning-Ping Foo, 2022. "Risk of Mortality in Association with Pregnancy in Women Following Motor Vehicle Crashes: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 19(2), pages 1-10, January.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:2:p:911-:d:724839
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    References listed on IDEAS

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    1. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
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