IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i12p7170-d836559.html
   My bibliography  Save this article

Dengue Seroprevalence and Factors Associated with Dengue Seropositivity in Petaling District, Malaysia

Author

Listed:
  • Rui Jie Ng

    (Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
    These authors contributed equally to this work.)

  • Zhuo Lin Chong

    (Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Shah Alam 40170, Malaysia
    These authors contributed equally to this work.)

  • Mohd Hatta Abdul Mutalip

    (Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Shah Alam 40170, Malaysia)

  • Chiu-Wan Ng

    (Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia)

Abstract

Dengue virus (DENV) infection is a major public health concern, posing huge economic and disease burdens globally. In Malaysia, the incidence of DENV infections has increased significantly over the years. Nevertheless, the passive surveillance mechanism applied may not capture the actual magnitude of DENV infection. There was also a paucity of community-based studies exploring DENV seroprevalence. This study aimed to determine the DENV seroprevalence and the associated factors among the urban population in Petaling district, Malaysia. A population-based cross-sectional study was conducted from 18 August to 26 October 2018 with 533 participants recruited. Blood samples were collected and analysed for DENV seropositivity using a composite reference standard comprised of three dengue serological tests. Associated factors were identified by fitting Generalised Linear Mixed Models with binomial error structure and logit link function. DENV seroprevalence obtained was 79.0% (95% CI: 75.2–82.4%). The age-specific DENV seroprevalence showed an increasing trend with advancing age, from 22.7% (95% CI: 9.6–45.0%) for those aged below five years old to 94.9% (95% CI: 81.3–98.7%) for those aged ≥60 years old. Only age group and house level were found to be significant factors associated with DENV seropositivity. The odds of being DENV seropositive generally increased with age, from 13.43 (95% CI: 2.77–65.22) for the 5–9 years old age group to 384.77 (95% CI: 39.27–3769.97) for the ≥60 years old age group, as compared to those aged below 5 years old. For house level, those who lived on the first and second floor (OR: 8.98, 95% CI: 3.16–25.12) and the third floor and above (OR: 4.82, 95% CI: 1.89–12.32) had greater odds of being DENV seropositive compared to those living on the ground floor. This study demonstrated the persistently high DENV seroprevalence among the urban population in Petaling district, which could be useful to evaluate dengue control measures taken and estimate more accurate disease incidence. The associated factors with DENV seropositivity identified could also contribute to undertaking more targeted preventive and control measures.

Suggested Citation

  • Rui Jie Ng & Zhuo Lin Chong & Mohd Hatta Abdul Mutalip & Chiu-Wan Ng, 2022. "Dengue Seroprevalence and Factors Associated with Dengue Seropositivity in Petaling District, Malaysia," IJERPH, MDPI, vol. 19(12), pages 1-16, June.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7170-:d:836559
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/12/7170/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/12/7170/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Dyna Doum & Hans J. Overgaard & Mayfong Mayxay & Sutas Suttiprapa & Prasert Saichua & Tipaya Ekalaksananan & Panwad Tongchai & Md. Siddikur Rahman & Ubydul Haque & Sysavanh Phommachanh & Tiengkham Pon, 2020. "Dengue Seroprevalence and Seroconversion in Urban and Rural Populations in Northeastern Thailand and Southern Laos," IJERPH, MDPI, vol. 17(23), pages 1-19, December.
    2. Donald S Shepard & Eduardo A Undurraga & Yara A Halasa, 2013. "Economic and Disease Burden of Dengue in Southeast Asia," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 7(2), pages 1-12, February.
    3. Li Ping Wong & Sazaly AbuBakar & Karuthan Chinna, 2014. "Community Knowledge, Health Beliefs, Practices and Experiences Related to Dengue Fever and Its Association with IgG Seropositivity," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 8(5), pages 1-13, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Gerhart Knerer & Christine S M Currie & Sally C Brailsford, 2020. "The economic impact and cost-effectiveness of combined vector-control and dengue vaccination strategies in Thailand: results from a dynamic transmission model," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 14(10), pages 1-32, October.
    2. Mokhalad A. Majeed & Helmi Zulhaidi Mohd Shafri & Zed Zulkafli & Aimrun Wayayok, 2023. "A Deep Learning Approach for Dengue Fever Prediction in Malaysia Using LSTM with Spatial Attention," IJERPH, MDPI, vol. 20(5), pages 1-22, February.
    3. Renaud Marti & Zhichao Li & Thibault Catry & Emmanuel Roux & Morgan Mangeas & Pascal Handschumacher & Jean Gaudart & Annelise Tran & Laurent Demagistri & Jean-François Faure & José Joaquín Carvajal & , 2020. "A Mapping Review on Urban Landscape Factors of Dengue Retrieved from Earth Observation Data, GIS Techniques, and Survey Questionnaires," Post-Print hal-02682042, HAL.
    4. Bin Chen & Jun Yang & Lei Luo & Zhicong Yang & Qiyong Liu, 2016. "Who Is Vulnerable to Dengue Fever? A Community Survey of the 2014 Outbreak in Guangzhou, China," IJERPH, MDPI, vol. 13(7), pages 1-11, July.
    5. Jue Tao Lim & Borame Sue Lee Dickens & Lawrence Zheng Xiong Chew & Esther Li Wen Choo & Joel Ruihan Koo & Joel Aik & Lee Ching Ng & Alex R Cook, 2020. "Impact of sars-cov-2 interventions on dengue transmission," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 14(10), pages 1-17, October.
    6. Pi Guo & Tao Liu & Qin Zhang & Li Wang & Jianpeng Xiao & Qingying Zhang & Ganfeng Luo & Zhihao Li & Jianfeng He & Yonghui Zhang & Wenjun Ma, 2017. "Developing a dengue forecast model using machine learning: A case study in China," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 11(10), pages 1-22, October.
    7. Tanvir Abir & O’mezie Ekwudu & Nazmul Ahsan Kalimullah & Dewan Muhammad Nur-A Yazdani & Abdullah Al Mamun & Palash Basak & Uchechukwu Levi Osuagwu & P Yukthamarani Permarupan & Abdul Hasnat Milton & S, 2021. "Dengue in Dhaka, Bangladesh: Hospital-based cross-sectional KAP assessment at Dhaka North and Dhaka South City Corporation area," PLOS ONE, Public Library of Science, vol. 16(3), pages 1-17, March.
    8. Adriana Zubieta-Zavala & Malaquias López-Cervantes & Guillermo Salinas-Escudero & Adrian Ramírez-Chávez & José Ramos Castañeda & Sendy Isarel Hernández-Gaytán & Juan Guillermo López Yescas & Luis Durá, 2018. "Economic impact of dengue in Mexico considering reported cases for 2012 to 2016," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 12(12), pages 1-18, December.
    9. Huong Van Nguyen & Phung Quoc Tat Than & Tu Huu Nguyen & Giang Thu Vu & Chi Linh Hoang & Tung Thanh Tran & Nu Thi Truong & Son Hoang Nguyen & Huyen Phuc Do & Giang Hai Ha & Huong Lan Thi Nguyen & Anh , 2019. "Knowledge, Attitude and Practice about Dengue Fever among Patients Experiencing the 2017 Outbreak in Vietnam," IJERPH, MDPI, vol. 16(6), pages 1-12, March.
    10. Eduardo A Undurraga & Yara A Halasa & Donald S Shepard, 2013. "Use of Expansion Factors to Estimate the Burden of Dengue in Southeast Asia: A Systematic Analysis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 7(2), pages 1-15, February.
    11. Agustin L. Arcenas, 2016. "Climate Change, Dengue and the Economy: Ascertaining the Link Between Dengue and Climatic Conditions," UP School of Economics Discussion Papers 201601, University of the Philippines School of Economics.
    12. Leigh R Bowman & Sarah Donegan & Philip J McCall, 2016. "Is Dengue Vector Control Deficient in Effectiveness or Evidence?: Systematic Review and Meta-analysis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 10(3), pages 1-24, March.
    13. Le T P Nghiem & Tarek Soliman & Darren C J Yeo & Hugh T W Tan & Theodore A Evans & John D Mumford & Reuben P Keller & Richard H A Baker & Richard T Corlett & Luis R Carrasco, 2013. "Economic and Environmental Impacts of Harmful Non-Indigenous Species in Southeast Asia," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-9, August.
    14. Christopher Fitzpatrick & Alexander Haines & Mathieu Bangert & Andrew Farlow & Janet Hemingway & Raman Velayudhan, 2017. "An economic evaluation of vector control in the age of a dengue vaccine," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 11(8), pages 1-27, August.
    15. Xuan Deng & Rui Yan & Zi-qiao Li & Xue-wen Tang & Yang Zhou & Hanqing He, 2021. "Economic and disease burden of Japanese encephalitis in Zhejiang Province, 2013–2018," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 15(6), pages 1-16, June.
    16. Bach Xuan Tran & Giang Thu Vu & Long Hoang Nguyen & Anh Tuan Le Nguyen & Tung Thanh Tran & Binh Thanh Nguyen & Thao Phuong Thi Thai & Carl A. Latkin & Cyrus S. H. Ho & Roger C. M. Ho, 2018. "Cost-of-Illness and the Health-Related Quality of Life of Patients in the Dengue Fever Outbreak in Hanoi in 2017," IJERPH, MDPI, vol. 15(6), pages 1-9, June.
    17. Mohd ‘Ammar Ihsan Ahmad Zamzuri & Farah Nabila Abd Majid & Rahmat Dapari & Mohd Rohaizat Hassan & Abd Majid Mohd Isa, 2022. "Perceived Risk for Dengue Infection Mediates the Relationship between Attitude and Practice for Dengue Prevention: A Study in Seremban, Malaysia," IJERPH, MDPI, vol. 19(20), pages 1-17, October.
    18. Rhanye Mac Guad & Yuan Seng Wu & Yin Nwe Aung & Shamala Devi Sekaran & André Barretto Bruno Wilke & Wah Yun Low & Maw Shin Sim & Rogie Royce Carandang & Mohammad Saffree Jeffree & Hamed Taherdoost & C, 2021. "Different Domains of Dengue Research in Malaysia: A Systematic Review and Meta-Analysis of Questionnaire-Based Studies," IJERPH, MDPI, vol. 18(9), pages 1-30, April.
    19. Jian-Wei Xu & Hui Liu & Didan Ai & Yan Yu & Bian Yu, 2019. "The Shan people’s health beliefs, knowledge and perceptions of dengue in Eastern Shan Special Region IV, Myanmar," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 13(6), pages 1-15, June.
    20. Nghiem, Le T.P. & Soliman, Tarek & Yeo, Darren C. J. & Tan, Hugh T. W. & Evans, Theodore A. & Mumford, John D. & Keller, Reuben P. & Baker, Richard H. A. & Corlett, Richard T. & Carrasco, Luis R., 2013. "Economic and Environmental Impacts of Harmful Non-Indigenous Species in Southeast Asia," MPRA Paper 57760, University Library of Munich, Germany.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7170-:d:836559. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.