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Increased Risk of COVID-19 in Patients with Diabetes Mellitus—Current Challenges in Pathophysiology, Treatment and Prevention

Author

Listed:
  • Tomasz Gęca

    (Chair and Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 20-081 Lublin, Poland)

  • Kamila Wojtowicz

    (Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland)

  • Paweł Guzik

    (Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland)

  • Tomasz Góra

    (Clinical Department of Gynecology and Obstetrics, John Paul’s 2nd Municipal Hospital, 35-241 Rzeszow, Poland
    Chair and Department of Gynecology and Obstetrics, Jagiellonian University Medical College, 31-501 Krakow, Poland)

Abstract

Coronavirus disease—COVID-19 (coronavirus disease 2019) has become the cause of the global pandemic in the last three years. Its etiological factor is SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus type 2). Patients with diabetes (DM—diabetes mellitus), in contrast to healthy people not suffering from chronic diseases, are characterised by higher morbidity and mortality due to COVID-19. Patients who test positive for SARCoV-2 are at higher risk of developing hyperglycaemia. In this paper, we present, analyse and summarize the data on possible mechanisms underlying the increased susceptibility and mortality of patients with diabetes mellitus in the case of SARS-CoV-2 infection. However, further research is required to determine the optimal therapeutic management of patients with diabetes and COVID-19.

Suggested Citation

  • Tomasz Gęca & Kamila Wojtowicz & Paweł Guzik & Tomasz Góra, 2022. "Increased Risk of COVID-19 in Patients with Diabetes Mellitus—Current Challenges in Pathophysiology, Treatment and Prevention," IJERPH, MDPI, vol. 19(11), pages 1-17, May.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:11:p:6555-:d:825891
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    1. Wenhui Li & Michael J. Moore & Natalya Vasilieva & Jianhua Sui & Swee Kee Wong & Michael A. Berne & Mohan Somasundaran & John L. Sullivan & Katherine Luzuriaga & Thomas C. Greenough & Hyeryun Choe & M, 2003. "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus," Nature, Nature, vol. 426(6965), pages 450-454, November.
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    1. Nadya Keumala Fitri & Meliani Meliani & Kartini Marpaung & Raden Andika Dwi Cahyadi & Ranti Permatasari & Cut Meliza Zainumi & Inke Nadia Diniyanti Lubis, 2024. "Community Actions and Insights in the Battle against COVID-19 at the Start of the Pandemic: A District Study Observation from Medan, Indonesia," IJERPH, MDPI, vol. 21(4), pages 1-12, April.

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