IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i4p1488-d493440.html
   My bibliography  Save this article

Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study

Author

Listed:
  • Marco Farronato

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Carolina Dolci

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Elisa Boccalari

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Sara Izadi

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Luis Hernan Salvatierra Rios

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Maurizio Festa

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
    Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy)

  • Valentina Panetta

    (L’Altrastatistica Consultancy & Training, Biostatistics Office, 00175 Rome, Italy)

  • Danila De Vito

    (Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari “Aldo Moro”, 70124 Bari, Italy)

  • Gianluca Martino Tartaglia

    (Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy)

Abstract

At the end of 2019, a new disease caused by the novel coronavirus SARS-CoV-2 appeared in Wuhan Province in China. Children seemed to be infected less frequently than adults, and family clusters seemed to play an important role in the spread of the pandemic. The aim of this study is to evaluate the serological profile of children and young adults between 4 and 16 years of age in order to assess the transmission patterns of COVID-19 between cohabitants. The subjects lived with at least one cohabitant who tested positive for the disease using a nasopharyngeal swab. To avoid contact with the disease, families were interviewed by telephone. Forty-nine children and adolescents with a mean age of 11 years were then subjected to a rapid lateral flow chromatographic test. Of them, seven (14.3%) were immunoglobulin G (IgG)-positive, and four (8.2%) were immunoglobulin M (IgM)-positive. In total, 16.3% of the tested sample had antibodies against SARS-CoV-2: this may confirm the lower vulnerability of children to COVID-19, despite the small sample size. The time from the negativization of the cohabitant until the test day may have influenced the results, especially when this timeframe is wide.

Suggested Citation

  • Marco Farronato & Carolina Dolci & Elisa Boccalari & Sara Izadi & Luis Hernan Salvatierra Rios & Maurizio Festa & Valentina Panetta & Danila De Vito & Gianluca Martino Tartaglia, 2021. "Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study," IJERPH, MDPI, vol. 18(4), pages 1-12, February.
  • Handle: RePEc:gam:jijerp:v:18:y:2021:i:4:p:1488-:d:493440
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/4/1488/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/18/4/1488/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Peng Zhou & Xing-Lou Yang & Xian-Guang Wang & Ben Hu & Lei Zhang & Wei Zhang & Hao-Rui Si & Yan Zhu & Bei Li & Chao-Lin Huang & Hui-Dong Chen & Jing Chen & Yun Luo & Hua Guo & Ren-Di Jiang & Mei-Qin L, 2020. "Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin," Nature, Nature, vol. 588(7836), pages 6-6, December.
    2. Peng Zhou & Xing-Lou Yang & Xian-Guang Wang & Ben Hu & Lei Zhang & Wei Zhang & Hao-Rui Si & Yan Zhu & Bei Li & Chao-Lin Huang & Hui-Dong Chen & Jing Chen & Yun Luo & Hua Guo & Ren-Di Jiang & Mei-Qin L, 2020. "A pneumonia outbreak associated with a new coronavirus of probable bat origin," Nature, Nature, vol. 579(7798), pages 270-273, March.
    3. Marco Farronato & Santosh K Tadakamadla & Mir Faeq Ali Quadri & Shashidhar Acharya & Jyothi Tadakamadla & Robert M. Love & Mohamed Jamal & Riaan Mulder & Cinzia Maspero & Davide Farronato & Alexander , 2020. "A Call for Action to Safely Deliver Oral Health Care during and Post COVID-19 Pandemic," IJERPH, MDPI, vol. 17(18), pages 1-11, September.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Nunzio Cirulli & Alessio Danilo Inchingolo & Assunta Patano & Sabino Ceci & Grazia Marinelli & Giuseppina Malcangi & Giovanni Coloccia & Valentina Montenegro & Chiara Di Pede & Anna Maria Ciocia & Giu, 2022. "Innovative Application of Diathermy in Orthodontics: A Case Report," IJERPH, MDPI, vol. 19(12), pages 1-11, June.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Shahadat Uddin & Arif Khan & Haohui Lu & Fangyu Zhou & Shakir Karim, 2022. "Suburban Road Networks to Explore COVID-19 Vulnerability and Severity," IJERPH, MDPI, vol. 19(4), pages 1-9, February.
    2. Kirsten R.C. Hensgens & Inge H.T. van Rensen & Anita W. Lekx & Frits H.M. van Osch & Lieve H.H. Knarren & Caroline E. Wyers & Joop P. van den Bergh & Dennis G. Barten, 2021. "Sort and Sieve: Pre-Triage Screening of Patients with Suspected COVID-19 in the Emergency Department," IJERPH, MDPI, vol. 18(17), pages 1-11, September.
    3. Quan-Hoang Vuong & Tam-Tri Le & Viet-Phuong La & Huyen Thanh Thanh Nguyen & Manh-Toan Ho & Quy Khuc & Minh-Hoang Nguyen, 2022. "Covid-19 vaccines production and societal immunization under the serendipity-mindsponge-3D knowledge management theory and conceptual framework," Palgrave Communications, Palgrave Macmillan, vol. 9(1), pages 1-12, December.
    4. Hengrui Liu & Sho Iketani & Arie Zask & Nisha Khanizeman & Eva Bednarova & Farhad Forouhar & Brandon Fowler & Seo Jung Hong & Hiroshi Mohri & Manoj S. Nair & Yaoxing Huang & Nicholas E. S. Tay & Sumin, 2022. "Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    5. Graziella Orrù & Ciro Conversano & Eleonora Malloggi & Francesca Francesconi & Rebecca Ciacchini & Angelo Gemignani, 2020. "Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review," IJERPH, MDPI, vol. 17(18), pages 1-18, September.
    6. Gleidson Sobreira Leite & Adriano Bessa Albuquerque & Plácido Rogerio Pinheiro, 2021. "Applications of Technological Solutions in Primary Ways of Preventing Transmission of Respiratory Infectious Diseases—A Systematic Literature Review," IJERPH, MDPI, vol. 18(20), pages 1-50, October.
    7. Britton Boras & Rhys M. Jones & Brandon J. Anson & Dan Arenson & Lisa Aschenbrenner & Malina A. Bakowski & Nathan Beutler & Joseph Binder & Emily Chen & Heather Eng & Holly Hammond & Jennifer Hammond , 2021. "Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
    8. Susanne Kessler & Bradly Burke & Geoffroy Andrieux & Jan Schinköthe & Lea Hamberger & Johannes Kacza & Shijun Zhan & Clara Reasoner & Taru S. Dutt & Maria Kaukab Osman & Marcela Henao-Tamayo & Julian , 2024. "Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    9. Yongzhu Xiong & Yunpeng Wang & Feng Chen & Mingyong Zhu, 2020. "Spatial Statistics and Influencing Factors of the COVID-19 Epidemic at Both Prefecture and County Levels in Hubei Province, China," IJERPH, MDPI, vol. 17(11), pages 1-26, May.
    10. Eugene Song & Jae-Eun Lee & Seola Kwon, 2021. "Effect of Public Empathy with Infection-Control Guidelines on Infection-Prevention Attitudes and Behaviors: Based on the Case of COVID-19," IJERPH, MDPI, vol. 18(24), pages 1-18, December.
    11. Fabiana Fiasca & Mauro Minelli & Dominga Maio & Martina Minelli & Ilaria Vergallo & Stefano Necozione & Antonella Mattei, 2020. "Associations between COVID-19 Incidence Rates and the Exposure to PM2.5 and NO 2 : A Nationwide Observational Study in Italy," IJERPH, MDPI, vol. 17(24), pages 1-10, December.
    12. Małgorzata Dudzińska & Marta Gwiaździńska-Goraj & Aleksandra Jezierska-Thöle, 2022. "Social Factors as Major Determinants of Rural Development Variation for Predicting Epidemic Vulnerability: A Lesson for the Future," IJERPH, MDPI, vol. 19(21), pages 1-24, October.
    13. James, Nick & Menzies, Max, 2023. "Collective infectivity of the pandemic over time and association with vaccine coverage and economic development," Chaos, Solitons & Fractals, Elsevier, vol. 176(C).
    14. Jaeyong Lee & Calem Kenward & Liam J. Worrall & Marija Vuckovic & Francesco Gentile & Anh-Tien Ton & Myles Ng & Artem Cherkasov & Natalie C. J. Strynadka & Mark Paetzel, 2022. "X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    15. Xu, Baochang & Li, Sihui & Afzal, Ayesha & Mirza, Nawazish & Zhang, Meng, 2022. "The impact of financial development on environmental sustainability: A European perspective," Resources Policy, Elsevier, vol. 78(C).
    16. Leili Mohammadi & Ahmad Mehravaran & Zahra Derakhshan & Ehsan Gharehchahi & Elza Bontempi & Mohammad Golaki & Razieh Khaksefidi & Mohadeseh Motamed-Jahromi & Mahsa Keshtkar & Amin Mohammadpour & Hamid, 2022. "Investigating the Role of Environmental Factors on the Survival, Stability, and Transmission of SARS-CoV-2, and Their Contribution to COVID-19 Outbreak: A Review," Sustainability, MDPI, vol. 14(18), pages 1-16, September.
    17. Jing Wang & Yuan-fei Pan & Li-fen Yang & Wei-hong Yang & Kexin Lv & Chu-ming Luo & Juan Wang & Guo-peng Kuang & Wei-chen Wu & Qin-yu Gou & Gen-yang Xin & Bo Li & Huan-le Luo & Shoudeng Chen & Yue-long, 2023. "Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    18. Nur Hannani Bi Rahman & Shazmin Shareena A. Azis & Ibrahim Sipan, 2021. "COVID-19: Standard Operating Procedure Improvement For Green Office Building Using Indoor Environmental Quality," LARES lares-2021-4dqg, Latin American Real Estate Society (LARES).
    19. Ho‐fung Hung, 2022. "The Virus, the Dollar, and the Global Order: The COVID‐19 Crisis in Comparative Perspective," Development and Change, International Institute of Social Studies, vol. 53(6), pages 1177-1199, November.
    20. Eduardo Gutiérrez-Abejón & Eduardo Tamayo & Débora Martín-García & F. Javier Álvarez & Francisco Herrera-Gómez, 2020. "Clinical Profile, Treatment and Predictors during the First COVID-19 Wave: A Population-Based Registry Analysis from Castile and Leon Hospitals," IJERPH, MDPI, vol. 17(24), pages 1-15, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:4:p:1488-:d:493440. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.