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Tetanus Vaccination and Extra-Immunization among Adult Populations: Eight-Year Follow Up Cohort Study of 771,443 Adults in Taiwan, 2006–2013

Author

Listed:
  • Shih-Wei Liu

    (Department of Emergency Medicine, National Yang-Ming University Hospital, I-Lan 26042, Taiwan)

  • Liang-Chung Huang

    (Department of Emergency Medicine, National Yang-Ming University Hospital, I-Lan 26042, Taiwan)

  • Wu-Fu Chung

    (Department of Emergency Medicine, National Yang-Ming University Hospital, I-Lan 26042, Taiwan
    School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan)

  • Jauching Wu

    (School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan
    Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 11217, Taiwan)

  • Li-Fu Chen

    (Department of Emergency Medicine, National Yang-Ming University Hospital, I-Lan 26042, Taiwan
    School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan)

  • Yu-Chun Chen

    (School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan
    Institute of Hospital and Health Care Administration, National Yang-Ming University, Taipei 11221, Taiwan
    Department of Family Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan)

Abstract

Under-and extra-immunization of tetanus boosters are important issues to consider in reducing the burden of vaccine-preventable disease in adults. The present study aimed to analyze the trend of vaccination coverage (VC) and risk factors associated with extra-immunization of tetanus during an 8-year period using a national-scale cohort database. Taiwan’s one-million representative research database, the Longitudinal Health Insurance Database (LHID2005) was used. A total of 771,443 adults aged between 20 and 79 years were enrolled and followed from 1 January 2006 to 31 December 2013. VC at the beginning was as low as 35.1%, declining gradually and dropping to 33.9% at the end of follow-up. While a total of 303,480 tetanus boosters were used during the study period, more than half (55.5%) of these boosters were considered as extra-immunized. Both individual characteristics and visit characteristics were strongly associated with extra-immunization. Males, young and older adults, and those with a higher number of comorbidities were more likely to receive extra-immunization boosters, especially when they had more severe symptoms, visited an emergency room, or visited a hospital with lower accreditation levels located in a less urbanized area. This information could enhance implementation of evidence-based programs for tetanus boosters.

Suggested Citation

  • Shih-Wei Liu & Liang-Chung Huang & Wu-Fu Chung & Jauching Wu & Li-Fu Chen & Yu-Chun Chen, 2018. "Tetanus Vaccination and Extra-Immunization among Adult Populations: Eight-Year Follow Up Cohort Study of 771,443 Adults in Taiwan, 2006–2013," IJERPH, MDPI, vol. 15(8), pages 1-11, August.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:8:p:1622-:d:161165
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    References listed on IDEAS

    as
    1. Yu-Chun Chen & Hsiao-Yun Yeh & Jau-Ching Wu & Ingo Haschler & Tzeng-Ji Chen & Thomas Wetter, 2011. "Taiwan’s National Health Insurance Research Database: administrative health care database as study object in bibliometrics," Scientometrics, Springer;Akadémiai Kiadó, vol. 86(2), pages 365-380, February.
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