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Simultaneous confidence bands for ratios of survival functions via empirical likelihood

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  • McKeague, Ian W.
  • Zhao, Yichuan

Abstract

We derive a simultaneous confidence band for the ratio of two survival functions based on independent right-censored data. Earlier authors have studied such bands for the difference of two survival functions, but the ratio provides a more appropriate comparison in some applications, e.g., in comparing two treatments in biomedical settings. Our approach is formulated in terms of empirical likelihood and allows us to avoid the use of simulation techniques that are often needed for Wald-type confidence bands. By the transformation-preserving property we also obtain confidence bands for the difference in the cumulative hazard functions. The approach is illustrated with a real data example.

Suggested Citation

  • McKeague, Ian W. & Zhao, Yichuan, 2002. "Simultaneous confidence bands for ratios of survival functions via empirical likelihood," Statistics & Probability Letters, Elsevier, vol. 60(4), pages 405-415, December.
    • Handle: RePEc:eee:stapro:v:60:y:2002:i:4:p:405-415
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    References listed on IDEAS

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    1. Li, Gang, 1995. "On nonparametric likelihood ratio estimation of survival probabilities for censored data," Statistics & Probability Letters, Elsevier, vol. 25(2), pages 95-104, November.
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    Cited by:

    1. Yang, Hanfang & Zhao, Yichuan, 2012. "Smoothed empirical likelihood for ROC curves with censored data," Journal of Multivariate Analysis, Elsevier, vol. 109(C), pages 254-263.
    2. T. Chen & S. Tracy & H. Uno, 2021. "OptBand: optimization-based confidence bands for functions to characterize time-to-event distributions," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(3), pages 481-498, July.
    3. Yanqing Sun & Rajeshwari Sundaram & Yichuan Zhao, 2009. "Empirical Likelihood Inference for the Cox Model with Time‐dependent Coefficients via Local Partial Likelihood," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 36(3), pages 444-462, September.
    4. Zhao, Meng & Zhao, Yichuan & McKeague, Ian W., 2015. "Empirical likelihood inference for the odds ratio of two survival functions under right censoring," Statistics & Probability Letters, Elsevier, vol. 107(C), pages 304-312.
    5. Zhao, Yichuan & Chen, Feiming, 2008. "Empirical likelihood inference for censored median regression model via nonparametric kernel estimation," Journal of Multivariate Analysis, Elsevier, vol. 99(2), pages 215-231, February.
    6. Shihong Zhu & Yifan Yang & Mai Zhou, 2015. "A note on the empirical likelihood confidence band for hazards ratio with covariate adjustment," Biometrics, The International Biometric Society, vol. 71(3), pages 859-563, September.
    7. Jimin Lee & Seunggeun Hyun, 2011. "Confidence bands for the difference of two survival functions under the additive risk model," Journal of Applied Statistics, Taylor & Francis Journals, vol. 38(4), pages 785-797, February.
    8. Nubyra Ahmed & Sundarraman Subramanian, 2016. "Semiparametric simultaneous confidence bands for the difference of survival functions," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 22(4), pages 504-530, October.
    9. Yichuan Zhao & Ali Jinnah, 2012. "Inference for Cox’s regression models via adjusted empirical likelihood," Computational Statistics, Springer, vol. 27(1), pages 1-12, March.
    10. Zhao, Yichuan, 2010. "Semiparametric inference for transformation models via empirical likelihood," Journal of Multivariate Analysis, Elsevier, vol. 101(8), pages 1846-1858, September.
    11. Sundarraman Subramanian, 2020. "Function-based hypothesis testing in censored two-sample location-scale models," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(1), pages 183-213, January.
    12. Bin Dong & David E. Matthews, 2012. "Empirical Likelihood for Cumulative Hazard Ratio Estimation with Covariate Adjustment," Biometrics, The International Biometric Society, vol. 68(2), pages 408-418, June.
    13. Robert Drake & Apratim Guha, 2014. "A mutual information-based k -sample test for discrete distributions," Journal of Applied Statistics, Taylor & Francis Journals, vol. 41(9), pages 2011-2027, September.
    14. Cheng, Guang & Zhao, Yichuan & Li, Bo, 2012. "Empirical likelihood inferences for the semiparametric additive isotonic regression," Journal of Multivariate Analysis, Elsevier, vol. 112(C), pages 172-182.
    15. McKeague, Ian W. & Zhao, Yichuan, 2006. "Width-scaled confidence bands for survival functions," Statistics & Probability Letters, Elsevier, vol. 76(4), pages 327-339, February.
    16. Qin, Gengsheng & Zhao, Yichuan, 2007. "Empirical likelihood inference for the mean residual life under random censorship," Statistics & Probability Letters, Elsevier, vol. 77(5), pages 549-557, March.
    17. Subramanian, Sundarraman, 2022. "Simultaneous confidence bands for survival functions from twice censorship," Statistics & Probability Letters, Elsevier, vol. 186(C).
    18. Yichuan Zhao & Song Yang, 2008. "Empirical likelihood inference for censored median regression with weighted empirical hazard functions," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 60(2), pages 441-457, June.
    19. Zhou, Mai & Zhu, Shihong, 2015. "Empirical likelihood confidence band for the difference of survival functions under proportional hazards model," Statistics & Probability Letters, Elsevier, vol. 107(C), pages 228-235.
    20. Guanghui Wei & Douglas E. Schaubel, 2008. "Estimating Cumulative Treatment Effects in the Presence of Nonproportional Hazards," Biometrics, The International Biometric Society, vol. 64(3), pages 724-732, September.
    21. Zhao, Yichuan & Zhao, Meng, 2011. "Empirical likelihood for the contrast of two hazard functions with right censoring," Statistics & Probability Letters, Elsevier, vol. 81(3), pages 392-401, March.
    22. Shen, Junshan & He, Shuyuan, 2006. "Empirical likelihood for the difference of two survival functions under right censorship," Statistics & Probability Letters, Elsevier, vol. 76(2), pages 169-181, January.

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