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Analysis of long series of longitudinal ordinal data using marginalized models

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  • Lee, Keunbaik
  • Sohn, Insuk
  • Kim, Donguk

Abstract

Marginalized models (Heagerty, 1999, 2002) are often used for short longitudinal series when population averaged effects are of interest. Lee and Daniels (2007, 2008) proposed marginalized models for the analysis of longitudinal ordinal data to permit likelihood-based estimation of marginal mean parameters. In this paper, we extend their work to accommodate the response dependence that we have seen with long series of response data (the functional form of response dependence has both serial and long-range components). Maximum likelihood estimation is proposed utilizing the Quasi-Newton algorithm with a Quasi Monte Carlo method for integration of the random effects. The methods are illustrated on quality of life data from a recent lung cancer clinical trial.

Suggested Citation

  • Lee, Keunbaik & Sohn, Insuk & Kim, Donguk, 2016. "Analysis of long series of longitudinal ordinal data using marginalized models," Computational Statistics & Data Analysis, Elsevier, vol. 94(C), pages 363-371.
    • Handle: RePEc:eee:csdana:v:94:y:2016:i:c:p:363-371
    DOI: 10.1016/j.csda.2015.07.010
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    References listed on IDEAS

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    1. Jonathan S. Schildcrout & Patrick J. Heagerty, 2007. "Marginalized Models for Moderate to Long Series of Longitudinal Binary Response Data," Biometrics, The International Biometric Society, vol. 63(2), pages 322-331, June.
    2. Robert Gibbons & R. Bock, 1987. "Trend in correlated proportions," Psychometrika, Springer;The Psychometric Society, vol. 52(1), pages 113-124, March.
    3. Patrick J. Heagerty, 2002. "Marginalized Transition Models and Likelihood Inference for Longitudinal Categorical Data," Biometrics, The International Biometric Society, vol. 58(2), pages 342-351, June.
    4. Patrick J. Heagerty, 1999. "Marginally Specified Logistic-Normal Models for Longitudinal Binary Data," Biometrics, The International Biometric Society, vol. 55(3), pages 688-698, September.
    5. Keunbaik Lee & Michael J. Daniels, 2007. "A Class of Markov Models for Longitudinal Ordinal Data," Biometrics, The International Biometric Society, vol. 63(4), pages 1060-1067, December.
    6. Lee, Keunbaik & Mercante, Donald, 2010. "Longitudinal nominal data analysis using marginalized models," Computational Statistics & Data Analysis, Elsevier, vol. 54(1), pages 208-218, January.
    7. Keunbaik Lee & Sanggil Kang & Xuefeng Liu & Daekwan Seo, 2011. "Likelihood-based approach for analysis of longitudinal nominal data using marginalized random effects models," Journal of Applied Statistics, Taylor & Francis Journals, vol. 38(8), pages 1577-1590, July.
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    Cited by:

    1. Lee, Keunbaik & Joo, Yongsung, 2019. "Marginalized models for longitudinal count data," Computational Statistics & Data Analysis, Elsevier, vol. 136(C), pages 47-58.

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