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A class of transformed hazards models for recurrent gap times

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  • Kang, Fangyuan
  • Sun, Liuquan
  • Zhao, Xingqiu

Abstract

In this article, a class of transformed hazards models is proposed for recurrent gap time data, including both the proportional and additive hazards models as special cases. An estimating equation-based inference procedure is developed for the model parameters, and the asymptotic properties of the resulting estimators are established. In addition, a lack-of-fit test is presented to assess the adequacy of the model. The finite sample behavior of the proposed estimators is evaluated through simulation studies, and an application to a clinic study on chronic granulomatous disease (CGD) is illustrated.

Suggested Citation

  • Kang, Fangyuan & Sun, Liuquan & Zhao, Xingqiu, 2015. "A class of transformed hazards models for recurrent gap times," Computational Statistics & Data Analysis, Elsevier, vol. 83(C), pages 151-167.
  • Handle: RePEc:eee:csdana:v:83:y:2015:i:c:p:151-167
    DOI: 10.1016/j.csda.2014.10.005
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    References listed on IDEAS

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    1. Zeng, Donglin & Yin, Guosheng & Ibrahim, Joseph G., 2005. "Inference for a Class of Transformed Hazards Models," Journal of the American Statistical Association, American Statistical Association, vol. 100, pages 1000-1008, September.
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    4. D. Y. Lin & L. J. Wei & I. Yang & Z. Ying, 2000. "Semiparametric regression for the mean and rate functions of recurrent events," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 62(4), pages 711-730.
    5. Xuelin Huang & Lei Liu, 2007. "A Joint Frailty Model for Survival and Gap Times Between Recurrent Events," Biometrics, The International Biometric Society, vol. 63(2), pages 389-397, June.
    6. Torben Martinussen & Thomas H. Scheike & Ib M. Skovgaard, 2002. "Efficient Estimation of Fixed and Time‐varying Covariate Effects in Multiplicative Intensity Models," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 29(1), pages 57-74, March.
    7. Kani Chen, 2002. "Semiparametric analysis of transformation models with censored data," Biometrika, Biometrika Trust, vol. 89(3), pages 659-668, August.
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