Optimal dose de-escalation trial designs for novel contraceptives in women
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DOI: 10.1016/j.csda.2011.08.005
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- Ying Kuen Cheung & Rick Chappell, 2000. "Sequential Designs for Phase I Clinical Trials with Late-Onset Toxicities," Biometrics, The International Biometric Society, vol. 56(4), pages 1177-1182, December.
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Keywords
Group-sequential design; Dose de-escalation; Dose finding; Contraception; Pearl Index; Continual reassessment method; 3+3 design;All these keywords.
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