IDEAS home Printed from https://ideas.repec.org/a/eee/chsofr/v92y2016icp91-100.html
   My bibliography  Save this article

Stochastic resonance in a genetic toggle model with harmonic excitation and Lévy noise

Author

Listed:
  • Xu, Yong
  • Wu, Juan
  • Du, Lin
  • Yang, Hui

Abstract

Stochastic resonance is investigated to explain the beneficial effect of Lévy noise on gene expression of genetic toggle model with harmonic excitation. The dynamic change of protein concentration of genetic toggle model under combined drives of harmonic excitation and Lévy noise is obtained numerically. Stochastic resonance is presented through the classical measure of signal-to-noise-ratio. Then from two aspects of combined drives on the protein at high or low concentration, the changes of protein concentration and signal-to-noise-ratio are discussed, respectively. When combined drives are within the protein at high concentration, the increasing Lévy noise intensity can promote the transition between the high and low concentrations, and the low protein concentration hardly fluctuates under the small noise intensity. It is also shown that the increase of stability index, skewness parameter of Lévy noise and amplitude of harmonic excitation can suppress the optimum collaboration of stochastic resonance. On the other hand, when combined drives are within the protein at lowconcentration, the increasing noise intensity can enhance the transition between the high and low concentrations, and the increase of stability index, skewness parameter and amplitude can strengthen the optimum collaboration of stochastic resonance. By the synergic actions of stochastic resonance, it is demonstrated that combined effect of harmonic excitation and Lévy stimuli can be utilized to promote the gene expression of proteins in genetic toggle model.

Suggested Citation

  • Xu, Yong & Wu, Juan & Du, Lin & Yang, Hui, 2016. "Stochastic resonance in a genetic toggle model with harmonic excitation and Lévy noise," Chaos, Solitons & Fractals, Elsevier, vol. 92(C), pages 91-100.
    • Handle: RePEc:eee:chsofr:v:92:y:2016:i:c:p:91-100
    DOI: 10.1016/j.chaos.2016.09.015
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0960077916302685
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.chaos.2016.09.015?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Aleksander Janicki & Aleksander Weron, 1994. "Simulation and Chaotic Behavior of Alpha-stable Stochastic Processes," HSC Books, Hugo Steinhaus Center, Wroclaw University of Science and Technology, number hsbook9401, December.
    2. Xu, Yong & Zhu, Ya-nan & Shen, Jianwei & Su, Jianbin, 2014. "Switch dynamics for stochastic model of genetic toggle switch," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 416(C), pages 461-466.
    3. S. Spezia & L. Curcio & A. Fiasconaro & N. Pizzolato & D. Valenti & B. Spagnolo & P. Bue & E. Peri & S. Colazza, 2008. "Evidence of stochastic resonance in the mating behavior of Nezara viridula (L.)," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 65(3), pages 453-458, October.
    4. Baronchelli, Andrea & Radicchi, Filippo, 2013. "Lévy flights in human behavior and cognition," Chaos, Solitons & Fractals, Elsevier, vol. 56(C), pages 101-105.
    5. Deng, Bin & Wang, Lin & Wang, Jiang & Wei, Xi-le & Yu, Hai-tao, 2014. "Endogenous fields enhanced stochastic resonance in a randomly coupled neuronal network," Chaos, Solitons & Fractals, Elsevier, vol. 68(C), pages 30-39.
    6. Yong Xu & Juanjuan Li & Jing Feng & Huiqing Zhang & Wei Xu & Jinqiao Duan, 2013. "Lévy noise-induced stochastic resonance in a bistable system," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 86(5), pages 1-7, May.
    7. Surya G Nurzaman & Yoshio Matsumoto & Yutaka Nakamura & Kazumichi Shirai & Satoshi Koizumi & Hiroshi Ishiguro, 2011. "From Lévy to Brownian: A Computational Model Based on Biological Fluctuation," PLOS ONE, Public Library of Science, vol. 6(2), pages 1-11, February.
    8. Zhou, Peipei & Cai, Shuiming & Liu, Zengrong & Chen, Luonan & Wang, Ruiqi, 2013. "Coupling switches and oscillators as a means to shape cellular signals in biomolecular systems," Chaos, Solitons & Fractals, Elsevier, vol. 50(C), pages 115-126.
    9. Timothy S. Gardner & Charles R. Cantor & James J. Collins, 2000. "Construction of a genetic toggle switch in Escherichia coli," Nature, Nature, vol. 403(6767), pages 339-342, January.
    10. David F. Russell & Lon A. Wilkens & Frank Moss, 1999. "Use of behavioural stochastic resonance by paddle fish for feeding," Nature, Nature, vol. 402(6759), pages 291-294, November.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Wu, Juan & Xu, Yong & Ma, Shaojuan, 2019. "Realizing the transformation of logic gates in a genetic toggle system under Lévy noise," Chaos, Solitons & Fractals, Elsevier, vol. 119(C), pages 171-179.
    2. Jin, Yanfei & Wang, Heqiang, 2020. "Noise-induced dynamics in a Josephson junction driven by trichotomous noises," Chaos, Solitons & Fractals, Elsevier, vol. 133(C).
    3. Cao, Boqiang & Shan, Meijing & Zhang, Qimin & Wang, Weiming, 2017. "A stochastic SIS epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 127-143.
    4. Guo, Yong-Feng & Wei, Fang & Xi, Bei & Tan, Jian-Guo, 2018. "The instability probability density evolution of the bistable system driven by Gaussian colored noise and white noise," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 503(C), pages 200-208.
    5. Gong, Xulu & Xu, Pengfei & Liu, Di & Zhou, Biliu, 2023. "Stochastic resonance of multi-stable energy harvesting system with high-order stiffness from rotational environment," Chaos, Solitons & Fractals, Elsevier, vol. 172(C).
    6. Guo, Yongfeng & Wang, Linjie & Dong, Qiang & Lou, Xiaojuan, 2021. "Dynamical complexity of FitzHugh–Nagumo neuron model driven by Lévy noise and Gaussian white noise," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 181(C), pages 430-443.
    7. Guo, Yongfeng & Wang, Linjie & Wei, Fang & Tan, Jianguo, 2019. "Dynamical behavior of simplified FitzHugh-Nagumo neural system driven by Lévy noise and Gaussian white noise," Chaos, Solitons & Fractals, Elsevier, vol. 127(C), pages 118-126.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wu, Juan & Xu, Yong & Ma, Shaojuan, 2019. "Realizing the transformation of logic gates in a genetic toggle system under Lévy noise," Chaos, Solitons & Fractals, Elsevier, vol. 119(C), pages 171-179.
    2. Korneev, Ivan & Zakharova, Anna & Semenov, Vladimir V., 2024. "Lévy noise-induced coherence resonance: Numerical study versus experiment," Chaos, Solitons & Fractals, Elsevier, vol. 184(C).
    3. Ping, Zhu, 2023. "Analytical equivalent transformation method for nonlinear stochastic dynamics with multiple noises in high dimensions," Chaos, Solitons & Fractals, Elsevier, vol. 176(C).
    4. Makoto Maejima & Gennady Samorodnitsky, 1999. "Certain Probabilistic Aspects of Semistable Laws," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 51(3), pages 449-462, September.
    5. Lombardi, Marco J. & Calzolari, Giorgio, 2009. "Indirect estimation of [alpha]-stable stochastic volatility models," Computational Statistics & Data Analysis, Elsevier, vol. 53(6), pages 2298-2308, April.
    6. Härdle, Wolfgang Karl & Burnecki, Krzysztof & Weron, Rafał, 2004. "Simulation of risk processes," Papers 2004,01, Humboldt University of Berlin, Center for Applied Statistics and Economics (CASE).
    7. Shogo Yonekura & Yasuo Kuniyoshi, 2017. "Bodily motion fluctuation improves reaching success rate in a neurophysical agent via geometric-stochastic resonance," PLOS ONE, Public Library of Science, vol. 12(12), pages 1-16, December.
    8. Foad Shokrollahi & Marcin Marcin Magdziarz, 2020. "Equity warrant pricing under subdiffusive fractional Brownian motion of the short rate," Papers 2007.12228, arXiv.org, revised Nov 2020.
    9. Furrer, Hansjorg & Michna, Zbigniew & Weron, Aleksander, 1997. "Stable Lévy motion approximation in collective risk theory," Insurance: Mathematics and Economics, Elsevier, vol. 20(2), pages 97-114, September.
    10. Yu, Dong & Wang, Guowei & Ding, Qianming & Li, Tianyu & Jia, Ya, 2022. "Effects of bounded noise and time delay on signal transmission in excitable neural networks," Chaos, Solitons & Fractals, Elsevier, vol. 157(C).
    11. Avraham E Mayo & Yaakov Setty & Seagull Shavit & Alon Zaslaver & Uri Alon, 2006. "Plasticity of the cis-Regulatory Input Function of a Gene," PLOS Biology, Public Library of Science, vol. 4(4), pages 1-1, March.
    12. Ortobelli, Sergio & Rachev, Svetlozar & Schwartz, Eduardo, 2000. "The Problem of Optimal Asset Allocation with Stable Distributed Returns," University of California at Los Angeles, Anderson Graduate School of Management qt3zd6q86c, Anderson Graduate School of Management, UCLA.
    13. Michna, Zbigniew, 2008. "Asymptotic behavior of the supremum tail probability for anomalous diffusions," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 387(2), pages 413-417.
    14. Menn, Christian & Rachev, Svetlozar T., 2005. "A GARCH option pricing model with [alpha]-stable innovations," European Journal of Operational Research, Elsevier, vol. 163(1), pages 201-209, May.
    15. Żaba, Mariusz & Garbaczewski, Piotr & Stephanovich, Vladimir, 2013. "Lévy flights in confining environments: Random paths and their statistics," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(17), pages 3485-3496.
    16. Fateev, I. & Polezhaev, A., 2024. "Chimera states in a lattice of superdiffusively coupled neurons," Chaos, Solitons & Fractals, Elsevier, vol. 181(C).
    17. Kim, Panki, 2006. "Weak convergence of censored and reflected stable processes," Stochastic Processes and their Applications, Elsevier, vol. 116(12), pages 1792-1814, December.
    18. Yu, Dong & Wu, Yong & Yang, Lijian & Zhao, Yunjie & Jia, Ya, 2023. "Effect of topology on delay-induced multiple resonances in locally driven systems," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 609(C).
    19. Tomas Tokar & Jozef Ulicny, 2013. "The Mathematical Model of the Bcl-2 Family Mediated MOMP Regulation Can Perform a Non-Trivial Pattern Recognition," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-8, December.
    20. Xu, Yong & Feng, Jing & Li, JuanJuan & Zhang, Huiqing, 2013. "Stochastic bifurcation for a tumor–immune system with symmetric Lévy noise," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(20), pages 4739-4748.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:chsofr:v:92:y:2016:i:c:p:91-100. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thayer, Thomas R. (email available below). General contact details of provider: https://www.journals.elsevier.com/chaos-solitons-and-fractals .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.