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Linkage bias in estimating the association between childhood exposures and propensity to become a mother: an example of simple sensitivity analyses

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  • D. Nitsch
  • B. L. DeStavola
  • S. M. B. Morton
  • D. A. Leon

Abstract

Summary. Record linkage is a powerful tool to obtain individual follow‐up information that is held in routinely collected databases. However, this method is potentially limited not only by the quality of the original data but also by the temporal and geographic coverage of the routine data. Migration in particular is a factor that might introduce systematic bias even in analyses of data covering relatively large geographical areas. We describe a linkage application where emigration bias might be an issue and use the sensitivity analysis approach that has been described by Molenberghs and co‐workers and Kenward and co‐workers to assess the extent of this bias.

Suggested Citation

  • D. Nitsch & B. L. DeStavola & S. M. B. Morton & D. A. Leon, 2006. "Linkage bias in estimating the association between childhood exposures and propensity to become a mother: an example of simple sensitivity analyses," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 169(3), pages 493-505, July.
    • Handle: RePEc:bla:jorssa:v:169:y:2006:i:3:p:493-505
    DOI: 10.1111/j.1467-985X.2006.00400.x
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    References listed on IDEAS

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    1. Charles F. Manski, 1989. "Anatomy of the Selection Problem," Journal of Human Resources, University of Wisconsin Press, vol. 24(3), pages 343-360.
    2. Daniel O. Scharfstein & Charles F. Manski & James C. Anthony, 2004. "On the Construction of Bounds in Prospective Studies with Missing Ordinal Outcomes: Application to the Good Behavior Game Trial," Biometrics, The International Biometric Society, vol. 60(1), pages 154-164, March.
    3. Geert Verbeke & Geert Molenberghs & Herbert Thijs & Emmanuel Lesaffre & Michael G. Kenward, 2001. "Sensitivity Analysis for Nonrandom Dropout: A Local Influence Approach," Biometrics, The International Biometric Society, vol. 57(1), pages 7-14, March.
    4. Geert Molenberghs & Michael G. Kenward & Els Goetghebeur, 2001. "Sensitivity analysis for incomplete contingency tables: the Slovenian plebiscite case," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 50(1), pages 15-29.
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