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Why Sub-Group Analysis is Desired to be Performed?

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  • Sanjeev Sarmukaddam

    (Maharashtra Institute of Mental Health, India)

Abstract

The question “Is sub-group analysis desired to be performed?†is asked or raised very often. In my opinion, the answer is ‘yes’. Sub-group analyses should be performed. There are few important reasons for this affirmative answer. It is important to detect subsets of patients who benefit from some of the treatments even when overall there may not be statistically significant difference in the treatments. In several types of studies we may want to examine the consistency of an observed relation across two or more subgroups of the individuals studied. For example, in a clinical trial we might want to know if the observed treatment difference is the same for young and old patients or for different stages of disease at presentation. In such cases we are interested in examining whether one effect is modified by the value of another variable.

Suggested Citation

  • Sanjeev Sarmukaddam, 2017. "Why Sub-Group Analysis is Desired to be Performed?," Biostatistics and Biometrics Open Access Journal, Juniper Publishers Inc., vol. 2(2), pages 24-29, June.
    • Handle: RePEc:adp:jbboaj:v:2:y:2017:i:2:p:24-29
    DOI: 10.19080/BBOAJ.2017.02.555581
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    References listed on IDEAS

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    1. Werner Dinkelbach, 1967. "On Nonlinear Fractional Programming," Management Science, INFORMS, vol. 13(7), pages 492-498, March.
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