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PTEN/Akt Axis is Involved in Somatic Cell Reprogramming to Mouse iPS Cells

Author

Listed:
  • Tomoe Ueyama
  • Shu Nakao
  • Tasuku Tsukamoto
  • Dai Ihara
  • Yukihiro Harada
  • Yuka Akagi
  • Sae Nakagawa
  • Teruhisa Kawamura

    (Department of Biomedical Sciences, Japan)

  • Takahiro Sogo

    (Global Innovation Research Organization, Japan)

  • Yasuyuki S Kida

    (Research Center for Stem Cell Engineering, Japan)

Abstract

Induced pluripotent stem cells (iPSCs) are highly expected to apply for regeneration therapy and disease modeling, although the efficiency of reprogramming to iPSCs remains not high enough...

Suggested Citation

  • Tomoe Ueyama & Shu Nakao & Tasuku Tsukamoto & Dai Ihara & Yukihiro Harada & Yuka Akagi & Sae Nakagawa & Teruhisa Kawamura & Takahiro Sogo & Yasuyuki S Kida, 2018. "PTEN/Akt Axis is Involved in Somatic Cell Reprogramming to Mouse iPS Cells," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 11(5), pages 8789-8795, December.
    • Handle: RePEc:abf:journl:v:11:y:2018:i:5:p:8789-8795
    DOI: 10.26717/BJSTR.2018.11.002162
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    References listed on IDEAS

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    1. Jochen Utikal & Jose M. Polo & Matthias Stadtfeld & Nimet Maherali & Warakorn Kulalert & Ryan M. Walsh & Adam Khalil & James G. Rheinwald & Konrad Hochedlinger, 2009. "Immortalization eliminates a roadblock during cellular reprogramming into iPS cells," Nature, Nature, vol. 460(7259), pages 1145-1148, August.
    2. Ygal Haupt & Ruth Maya & Anat Kazaz & Moshe Oren, 1997. "Mdm2 promotes the rapid degradation of p53," Nature, Nature, vol. 387(6630), pages 296-299, May.
    3. Michael H. G. Kubbutat & Stephen N. Jones & Karen H. Vousden, 1997. "Regulation of p53 stability by Mdm2," Nature, Nature, vol. 387(6630), pages 299-303, May.
    4. Rosa M. Marión & Katerina Strati & Han Li & Matilde Murga & Raquel Blanco & Sagrario Ortega & Oscar Fernandez-Capetillo & Manuel Serrano & Maria A. Blasco, 2009. "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity," Nature, Nature, vol. 460(7259), pages 1149-1153, August.
    5. Teruhisa Kawamura & Jotaro Suzuki & Yunyuan V. Wang & Sergio Menendez & Laura Batlle Morera & Angel Raya & Geoffrey M. Wahl & Juan Carlos Izpisúa Belmonte, 2009. "Linking the p53 tumour suppressor pathway to somatic cell reprogramming," Nature, Nature, vol. 460(7259), pages 1140-1144, August.
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    More about this item

    Keywords

    Biomedical Sciences; Biomedical Research; Technical Research; Prostate cancer; PSMA-PET/CT; PSMA-SPECT/CT; PRRT; Textural parameters;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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