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Structure-based classification of tauopathies

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Cited by:

  1. Anton Lindberg & Emily Murrell & Junchao Tong & N. Scott Mason & Daniel Sohn & Johan Sandell & Peter Ström & Jeffrey S. Stehouwer & Brian J. Lopresti & Jenny Viklund & Samuel Svensson & Chester A. Mat, 2024. "Ligand-based design of [18F]OXD-2314 for PET imaging in non-Alzheimer’s disease tauopathies," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
  2. Kartikay Sharma & Fabian Stockert & Jayakrishna Shenoy & Mélanie Berbon & Muhammed Bilal Abdul-Shukkoor & Birgit Habenstein & Antoine Loquet & Matthias Schmidt & Marcus Fändrich, 2024. "Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils," Nature Communications, Nature, vol. 15(1), pages 1-8, December.
  3. Szymon W. Manka & Wenjuan Zhang & Adam Wenborn & Jemma Betts & Susan Joiner & Helen R. Saibil & John Collinge & Jonathan D. F. Wadsworth, 2022. "2.7 Å cryo-EM structure of ex vivo RML prion fibrils," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
  4. Vishruth Mullapudi & Jaime Vaquer-Alicea & Vaibhav Bommareddy & Anthony R. Vega & Bryan D. Ryder & Charles L. White & Marc. I. Diamond & Lukasz A. Joachimiak, 2023. "Network of hotspot interactions cluster tau amyloid folds," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
  5. Binh An Nguyen & Virender Singh & Shumaila Afrin & Anna Yakubovska & Lanie Wang & Yasmin Ahmed & Rose Pedretti & Maria del Carmen Fernandez-Ramirez & Preeti Singh & Maja Pękała & Luis O. Cabrera Herna, 2024. "Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
  6. Pijush Chakraborty & Gwladys Rivière & Alina Hebestreit & Alain Ibáñez Opakua & Ina M. Vorberg & Loren B. Andreas & Markus Zweckstetter, 2023. "Acetylation discriminates disease-specific tau deposition," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
  7. Nicolai Franzmeier & Matthias Brendel & Leonie Beyer & Luna Slemann & Gabor G. Kovacs & Thomas Arzberger & Carolin Kurz & Gesine Respondek & Milica J. Lukic & Davina Biel & Anna Rubinski & Lukas Front, 2022. "Tau deposition patterns are associated with functional connectivity in primary tauopathies," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
  8. Inbal Maniv & Mahasen Sarji & Anwar Bdarneh & Alona Feldman & Roi Ankawa & Elle Koren & Inbar Magid-Gold & Noa Reis & Despina Soteriou & Shiran Salomon-Zimri & Tali Lavy & Ellina Kesselman & Naama Koi, 2023. "Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  9. Benjamin C. Creekmore & Kathryn Kixmoeller & Ben E. Black & Edward B. Lee & Yi-Wei Chang, 2024. "Ultrastructure of human brain tissue vitrified from autopsy revealed by cryo-ET with cryo-plasma FIB milling," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
  10. Gregory E. Merz & Matthew J. Chalkley & Sophia K. Tan & Eric Tse & Joanne Lee & Stanley B. Prusiner & Nick A. Paras & William F. DeGrado & Daniel R. Southworth, 2023. "Stacked binding of a PET ligand to Alzheimer’s tau paired helical filaments," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
  11. Dhruva D. Dhavale & Alexander M. Barclay & Collin G. Borcik & Katherine Basore & Deborah A. Berthold & Isabelle R. Gordon & Jialu Liu & Moses H. Milchberg & Jennifer Y. O’Shea & Michael J. Rau & Zacha, 2024. "Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
  12. Luca Pinzi & Christian Conze & Nicolo Bisi & Gabriele Dalla Torre & Ahmed Soliman & Nanci Monteiro-Abreu & Nataliya I. Trushina & Andrea Krusenbaum & Maryam Khodaei Dolouei & Andrea Hellwig & Michael , 2024. "Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
  13. Nathalie Kyalu Ngoie Zola & Clémence Balty & Sébastien Pyr dit Ruys & Axelle A. T. Vanparys & Nicolas D. G. Huyghe & Gaëtan Herinckx & Manuel Johanns & Emilien Boyer & Pascal Kienlen-Campard & Mark H., 2023. "Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
  14. Peter Kunach & Jaime Vaquer-Alicea & Matthew S. Smith & Jim Monistrol & Robert Hopewell & Luc Moquin & Joseph Therriault & Cecile Tissot & Nesrine Rahmouni & Gassan Massarweh & Jean-Paul Soucy & Marie, 2024. "Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240," Nature Communications, Nature, vol. 15(1), pages 1-7, December.
  15. Tim Schulte & Antonio Chaves-Sanjuan & Valentina Speranzini & Kevin Sicking & Melissa Milazzo & Giulia Mazzini & Paola Rognoni & Serena Caminito & Paolo Milani & Chiara Marabelli & Alessandro Corbelli, 2024. "Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  16. Galina Limorenko & Meltem Tatli & Rajasekhar Kolla & Sergey Nazarov & Marie-Theres Weil & David C. Schöndorf & Daniela Geist & Peter Reinhardt & Dagmar E. Ehrnhoefer & Henning Stahlberg & Laura Gaspar, 2023. "Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
  17. Nikolaos Louros & Martin Wilkinson & Grigoria Tsaka & Meine Ramakers & Chiara Morelli & Teresa Garcia & Rodrigo Gallardo & Sam D’Haeyer & Vera Goossens & Dominique Audenaert & Dietmar Rudolf Thal & Ia, 2024. "Local structural preferences in shaping tau amyloid polymorphism," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
  18. Itika Saha & Patricia Yuste-Checa & Miguel Silva Padilha & Qiang Guo & Roman Körner & Hauke Holthusen & Victoria A. Trinkaus & Irina Dudanova & Rubén Fernández-Busnadiego & Wolfgang Baumeister & David, 2023. "The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
  19. Martin Wilkinson & Rodrigo U. Gallardo & Roberto Maya Martinez & Nicolas Guthertz & Masatomo So & Liam D. Aubrey & Sheena E. Radford & Neil A. Ranson, 2023. "Disease-relevant β2-microglobulin variants share a common amyloid fold," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
  20. Aurelio J. Dregni & Pu Duan & Hong Xu & Lakshmi Changolkar & Nadia El Mammeri & Virginia M.-Y. Lee & Mei Hong, 2022. "Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
  21. Dailu Chen & Sofia Bali & Ruhar Singh & Aleksandra Wosztyl & Vishruth Mullapudi & Jaime Vaquer-Alicea & Parvathy Jayan & Shamiram Melhem & Harro Seelaar & John C. Swieten & Marc I. Diamond & Lukasz A., 2023. "FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
  22. Jinjian Hu & Wencheng Xia & Shuyi Zeng & Yeh-Jun Lim & Youqi Tao & Yunpeng Sun & Lang Zhao & Haosen Wang & Weidong Le & Dan Li & Shengnan Zhang & Cong Liu & Yan-Mei Li, 2024. "Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
  23. Youqi Tao & Yunpeng Sun & Shiran Lv & Wencheng Xia & Kun Zhao & Qianhui Xu & Qinyue Zhao & Lin He & Weidong Le & Yong Wang & Cong Liu & Dan Li, 2022. "Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
  24. Sukanta Jash & Sayani Banerjee & Shibin Cheng & Bin Wang & Chenxi Qiu & Asami Kondo & Jan Ernerudh & Xiao Zhen Zhou & Kun Ping Lu & Surendra Sharma, 2023. "Cis P-tau is a central circulating and placental etiologic driver and therapeutic target of preeclampsia," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
  25. Levent Sari & Sofia Bali & Lukasz A. Joachimiak & Milo M. Lin, 2024. "Hairpin trimer transition state of amyloid fibril," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  26. Sambhasan Banerjee & Julian Baur & Christoph Daniel & Peter Benedikt Pfeiffer & Manuel Hitzenberger & Lukas Kuhn & Sebastian Wiese & Johan Bijzet & Christian Haupt & Kerstin U. Amann & Martin Zacharia, 2022. "Amyloid fibril structure from the vascular variant of systemic AA amyloidosis," Nature Communications, Nature, vol. 13(1), pages 1-8, December.
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