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Optimal Kidney Exchange with Immunosuppressants

Author

Listed:
  • Haris Aziz

    (School of Computer Science and Engineering, UNSW)

  • Agnes Cseh

    (Institute of Economics, Centre for Economic and Regional Studies)

Abstract

Potent immunosuppressant drugs suppress the body’s ability to reject a transplanted organ up to the point that a transplant across blood- or tissue-type incompatibility becomes possible. In contrast to the standard kidney exchange problem, our setting also involves the decision about which patients receive from the limited supply of immunosuppressants that make them compatible with originally incompatible kidneys. We firstly present a general computational framework to model this problem. Our main contribution is a range of efficient algorithms that provide flexibility in terms of meeting meaningful objectives. We also show that these algorithms satisfy desirable axiomatic and strategic properties.

Suggested Citation

  • Haris Aziz & Agnes Cseh, 2019. "Optimal Kidney Exchange with Immunosuppressants," CERS-IE WORKING PAPERS 1915, Institute of Economics, Centre for Economic and Regional Studies.
    • Handle: RePEc:has:discpr:1915
    as

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    References listed on IDEAS

    as
    1. Roth, Alvin E. & Sonmez, Tayfun & Utku Unver, M., 2005. "Pairwise kidney exchange," Journal of Economic Theory, Elsevier, vol. 125(2), pages 151-188, December.
    2. Alvin E. Roth & Tayfun Sönmez, 2005. "A Kidney Exchange Clearinghouse in New England," American Economic Review, American Economic Association, vol. 95(2), pages 376-380, May.
    3. Andersson, Tommy & Kratz, Jörgen, 2016. "Kidney Exchange over the Blood Group Barrier," Working Papers 2016:11, Lund University, Department of Economics, revised 29 Nov 2017.
    4. Hatfield, John William, 2005. "Pairwise kidney exchange: Comment," Journal of Economic Theory, Elsevier, vol. 125(2), pages 189-193, December.
    5. Eun Jeong Heo & Sunghoon Hong & Youngsub Chun, 2021. "Kidney exchange with immunosuppressants," Economic Theory, Springer;Society for the Advancement of Economic Theory (SAET), vol. 72(1), pages 1-19, July.
    6. Tayfun Sönmez & M. Utku Ünver, 2009. "Matching, Allocation, and Exchange of Discrete Resources," Boston College Working Papers in Economics 717, Boston College Department of Economics.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    Keywords

    kidney exchange; immunosuppressant drugs; matching; complexity;
    All these keywords.

    JEL classification:

    • C63 - Mathematical and Quantitative Methods - - Mathematical Methods; Programming Models; Mathematical and Simulation Modeling - - - Computational Techniques
    • C78 - Mathematical and Quantitative Methods - - Game Theory and Bargaining Theory - - - Bargaining Theory; Matching Theory

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