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Genome-wide Association Studies and the Genetics of Entrepreneurship

Author

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  • van der Loos, M.J.H.M.
  • Koellinger, Ph.D.
  • Groenen, P.J.F.
  • Thurik, A.R.

Abstract

We are currently investigating genetic influences on self-employment in an international research consortium using genome-wide association studies (GWAS). By meta-analysing results from numerous independent samples we address identification issues arising from multiple testing. To our knowledge, this is the earliest attempt to apply GWAS to an economic outcome of a relatively general nature. Our study will reveal potentials and limitations of this approach for economic research.

Suggested Citation

  • van der Loos, M.J.H.M. & Koellinger, Ph.D. & Groenen, P.J.F. & Thurik, A.R., 2010. "Genome-wide Association Studies and the Genetics of Entrepreneurship," ERIM Report Series Research in Management ERS-2010-004-ORG, Erasmus Research Institute of Management (ERIM), ERIM is the joint research institute of the Rotterdam School of Management, Erasmus University and the Erasmus School of Economics (ESE) at Erasmus University Rotterdam.
    • Handle: RePEc:ems:eureri:17757
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    1. Schmitz, James A, Jr, 1989. "Imitation, Entrepreneurship, and Long-run Growth," Journal of Political Economy, University of Chicago Press, vol. 97(3), pages 721-739, June.
    2. Ari Hyytinen & Olli‐Pekka Ruuskanen, 2007. "Time Use of the Self‐Employed," Kyklos, Wiley Blackwell, vol. 60(1), pages 105-122, February.
    3. Martin Carree & A. R. Thurik (ed.), 2006. "Entrepreneurship and Economic Growth," Books, Edward Elgar Publishing, number 3673.
    4. Matthias Benz & Bruno S. Frey, 2008. "Being Independent is a Great Thing: Subjective Evaluations of Self‐Employment and Hierarchy," Economica, London School of Economics and Political Science, vol. 75(298), pages 362-383, May.
    5. Rablen, Matthew D. & Oswald, Andrew J., 2008. "Mortality and immortality: The Nobel Prize as an experiment into the effect of status upon longevity," Journal of Health Economics, Elsevier, vol. 27(6), pages 1462-1471, December.
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    Cited by:

    1. A. Roy Thurik & David B. Audretsch & Jörn H. Block & Andrew Burke & Martin A. Carree & Marcus Dejardin & Cornelius A. Rietveld & Mark Sanders & Ute Stephan & Johan Wiklund, 2024. "The impact of entrepreneurship research on other academic fields," Small Business Economics, Springer, vol. 62(2), pages 727-751, February.
    2. Hyytinen, Ari & Ilmakunnas, Pekka & Toivanen, Otto, 2013. "The return-to-entrepreneurship puzzle," Labour Economics, Elsevier, vol. 20(C), pages 57-67.
    3. Matthijs J H M van der Loos & Cornelius A Rietveld & Niina Eklund & Philipp D Koellinger & Fernando Rivadeneira & Gonçalo R Abecasis & Georgina A Ankra-Badu & Sebastian E Baumeister & Daniel J Benjami, 2013. "The Molecular Genetic Architecture of Self-Employment," PLOS ONE, Public Library of Science, vol. 8(4), pages 1-15, April.
    4. Rafael Ravina-Ripoll & María-José Foncubierta-Rodríguez & Eduardo Ahumada-Tello & Luis Bayardo Tobar-Pesantez, 2021. "Does Entrepreneurship Make You Happier? A Comparative Analysis between Entrepreneurs and Wage Earners," Sustainability, MDPI, vol. 13(18), pages 1-19, September.
    5. Wim Naudé & José Ernesto Amorós & Oscar Cristi, 2011. "‘Surfeiting, The Appetite May Sicken’: Entrepreneurship and the Happiness of Nations," Working Papers 2011/07, Maastricht School of Management.
    6. Philipp Koellinger & Matthijs Loos & Patrick Groenen & A. Thurik & Fernando Rivadeneira & Frank Rooij & André Uitterlinden & Albert Hofman, 2010. "Genome-wide association studies in economics and entrepreneurship research: promises and limitations," Small Business Economics, Springer, vol. 35(1), pages 1-18, July.
    7. Matthijs Loos & Philipp Koellinger & Patrick Groenen & Cornelius Rietveld & Fernando Rivadeneira & Frank Rooij & André Uitterlinden & Albert Hofman & A. Thurik, 2011. "Candidate gene studies and the quest for the entrepreneurial gene," Small Business Economics, Springer, vol. 37(3), pages 269-275, October.
    8. Cornelius A. Rietveld & Eric A.W. Slob & A. Roy Thurik, 2021. "A decade of research on the genetics of entrepreneurship: a review and view ahead," Small Business Economics, Springer, vol. 57(3), pages 1303-1317, October.
    9. Lerner, Daniel A. & Hatak, Isabella & Rauch, Andreas, 2018. "Deep roots? Behavioral Inhibition and Behavioral Activation System (BIS/BAS) sensitivity and entrepreneurship," Journal of Business Venturing Insights, Elsevier, vol. 9(C), pages 107-115.
    10. Wim Naudé & José Amorós & Oscar Cristi, 2014. "“Surfeiting, the appetite may sicken”: entrepreneurship and happiness," Small Business Economics, Springer, vol. 42(3), pages 523-540, March.
    11. Singer Burton, 2011. "Genome-Phenome Linkages in Human Population Surveys, with Special Emphasis on the Health and Retirement Survey," Forum for Health Economics & Policy, De Gruyter, vol. 14(2), pages 1-24, April.

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    More about this item

    Keywords

    entrepreneurship; genetics;

    JEL classification:

    • J24 - Labor and Demographic Economics - - Demand and Supply of Labor - - - Human Capital; Skills; Occupational Choice; Labor Productivity
    • L26 - Industrial Organization - - Firm Objectives, Organization, and Behavior - - - Entrepreneurship
    • M - Business Administration and Business Economics; Marketing; Accounting; Personnel Economics
    • M13 - Business Administration and Business Economics; Marketing; Accounting; Personnel Economics - - Business Administration - - - New Firms; Startups
    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D

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