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The elementary flux modes of a manufacturing system: a novel approach to explore the relationship of network structure and function

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  • Mirja Meyer
  • Marc-Thorsten Hütt
  • Julia Bendul

Abstract

Elementary flux modes (EFMs) are a concept from Systems Biology, where they serve as an indicator of component relevance in metabolic networks. An elementary flux mode is a functionally relevant, non-decomposable path through a given network. In this paper, we apply elementary flux mode analysis to manufacturing systems, with the aim of using the number of EFMs as a predictor for resource significance in the manufacturing system. For this, we formulate a network representation of a manufacturing process, which allows us to define the manufacturing equivalent of a stoichiometric matrix to draw an analogy between metabolic and manufacturing systems. This, in turn, allows the computation of EFMs, which we conduct in a case-study for a real manufacturing system. We further show that the change of EFMs under resource breakdown is a good indicator of the average order lateness in the manufacturing system. In this way, EFMs provide insight into the relationship of network structure and function in manufacturing.

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  • Mirja Meyer & Marc-Thorsten Hütt & Julia Bendul, 2016. "The elementary flux modes of a manufacturing system: a novel approach to explore the relationship of network structure and function," International Journal of Production Research, Taylor & Francis Journals, vol. 54(14), pages 4145-4160, July.
    • Handle: RePEc:taf:tprsxx:v:54:y:2015:i:14:p:4145-4160
    DOI: 10.1080/00207543.2015.1106612
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    Cited by:

    1. Yanlin Shi & Qingjin Peng, 2023. "Conceptual design of product structures based on WordNet hierarchy and association relation," Journal of Intelligent Manufacturing, Springer, vol. 34(6), pages 2655-2671, August.

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