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Development and validation of a computational model of the knee joint for the evaluation of surgical treatments for osteoarthritis

Author

Listed:
  • R. Mootanah
  • C.W. Imhauser
  • F. Reisse
  • D. Carpanen
  • R.W. Walker
  • M.F. Koff
  • M.W. Lenhoff
  • S.R. Rozbruch
  • A.T. Fragomen
  • Z. Dewan
  • Y.M. Kirane
  • K. Cheah
  • J.K. Dowell
  • H.J. Hillstrom

Abstract

A three-dimensional (3D) knee joint computational model was developed and validated to predict knee joint contact forces and pressures for different degrees of malalignment. A 3D computational knee model was created from high-resolution radiological images to emulate passive sagittal rotation (full-extension to 65°-flexion) and weight acceptance. A cadaveric knee mounted on a six-degree-of-freedom robot was subjected to matching boundary and loading conditions. A ligament-tuning process minimised kinematic differences between the robotically loaded cadaver specimen and the finite element (FE) model. The model was validated by measured intra-articular force and pressure measurements. Percent full scale error between FE-predicted and in vitro-measured values in the medial and lateral compartments were 6.67% and 5.94%, respectively, for normalised peak pressure values, and 7.56% and 4.48%, respectively, for normalised force values. The knee model can accurately predict normalised intra-articular pressure and forces for different loading conditions and could be further developed for subject-specific surgical planning.

Suggested Citation

  • R. Mootanah & C.W. Imhauser & F. Reisse & D. Carpanen & R.W. Walker & M.F. Koff & M.W. Lenhoff & S.R. Rozbruch & A.T. Fragomen & Z. Dewan & Y.M. Kirane & K. Cheah & J.K. Dowell & H.J. Hillstrom, 2014. "Development and validation of a computational model of the knee joint for the evaluation of surgical treatments for osteoarthritis," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 17(13), pages 1502-1517, October.
    • Handle: RePEc:taf:gcmbxx:v:17:y:2014:i:13:p:1502-1517
    DOI: 10.1080/10255842.2014.899588
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    1. Colin D Mathers & Dejan Loncar, 2006. "Projections of Global Mortality and Burden of Disease from 2002 to 2030," PLOS Medicine, Public Library of Science, vol. 3(11), pages 1-20, November.
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