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Locally optimal designs for comparing curves in generalized linear models

Author

Listed:
  • Chang-Yu Liu

    (Shanghai Normal University)

  • Xin Liu

    (Donghua University)

  • Rong-Xian Yue

    (Shanghai Normal University)

Abstract

This article is concerned with the optimal design problem of efficient statistical inference for comparing regression mean curves in two generalized linear models (GLMs) estimated from two samples of independent measurements. The main objective is to find the locally $$\mu _p$$ μ p -optimal designs for given values of the model parameters that minimize an $$L_p$$ L p -norm of the asymptotic variance of the difference between the two estimated regression curves. Two equivalence theorems are given to verify the locally $$\mu _p$$ μ p -optimality of the designs in the set of all approximate designs for the comparison of regression curves in two GLMs. Several numerical examples are presented to illustrate the superiorities of the locally $$\mu _p$$ μ p -optimal designs ( $$p=1,\infty $$ p = 1 , ∞ ) by comparing them with equidistant designs and individual D-optimal designs for the comparison of regression curves in different scenarios.

Suggested Citation

  • Chang-Yu Liu & Xin Liu & Rong-Xian Yue, 2024. "Locally optimal designs for comparing curves in generalized linear models," Statistical Papers, Springer, vol. 65(5), pages 3181-3201, July.
  • Handle: RePEc:spr:stpapr:v:65:y:2024:i:5:d:10.1007_s00362-023-01514-0
    DOI: 10.1007/s00362-023-01514-0
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    References listed on IDEAS

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    1. Liu W. & Jamshidian M. & Zhang Y., 2004. "Multiple Comparison of Several Linear Regression Models," Journal of the American Statistical Association, American Statistical Association, vol. 99, pages 395-403, January.
    2. Dette, Holger & Schorning, Kirsten & Konstantinou, Maria, 2017. "Optimal designs for comparing regression models with correlated observations," Computational Statistics & Data Analysis, Elsevier, vol. 113(C), pages 273-286.
    3. W. Liu & F. Bretz & A. J. Hayter & H. P. Wynn, 2009. "Assessing Nonsuperiority, Noninferiority, or Equivalence When Comparing Two Regression Models Over a Restricted Covariate Region," Biometrics, The International Biometric Society, vol. 65(4), pages 1279-1287, December.
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