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Modelling the Cost Effectiveness of Interventions for Osteoporosis: Issues to Consider

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  • Matt Stevenson
  • Peter Selby

Abstract

Expenditure on treating osteoporotic fractures and on preventative intervention is considerable and is likely to rise in forthcoming years due to the association between fracture risk and age. With funders such as the National Institute for Health and Care Excellence and the Pharmaceutical Benefits Advisory Committee explicitly considering cost-effectiveness analyses within the process of producing guidance, it is imperative that economic models are as robust as possible. This article details issues that need to be considered specifically related to health technology assessments of interventions for osteoporosis, and highlights limitations within the current evidence base. A likely direction of impact on cost effectiveness of addressing the key issues has been included alongside a tentative categorization of the level of these impacts. It is likely that cost-effectiveness ratios presented in previous models that did not address the identified issues were favourable to interventions. Copyright Springer International Publishing Switzerland 2014

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  • Matt Stevenson & Peter Selby, 2014. "Modelling the Cost Effectiveness of Interventions for Osteoporosis: Issues to Consider," PharmacoEconomics, Springer, vol. 32(8), pages 735-743, August.
    • Handle: RePEc:spr:pharme:v:32:y:2014:i:8:p:735-743
    DOI: 10.1007/s40273-014-0156-8
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    References listed on IDEAS

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    1. Karl Claxton & Mark Sculpher & Chris McCabe & Andrew Briggs & Ron Akehurst & Martin Buxton & John Brazier & Tony O'Hagan, 2005. "Probabilistic sensitivity analysis for NICE technology assessment: not an optional extra," Health Economics, John Wiley & Sons, Ltd., vol. 14(4), pages 339-347, April.
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    1. Mickaël Hiligsmann & Silvia Evers & Wafa Ben Sedrine & John Kanis & Bram Ramaekers & Jean-Yves Reginster & Stuart Silverman & Caroline Wyers & Annelies Boonen, 2015. "A Systematic Review of Cost-Effectiveness Analyses of Drugs for Postmenopausal Osteoporosis," PharmacoEconomics, Springer, vol. 33(3), pages 205-224, March.

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