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Sample Size and Power for Cost-Effectiveness Analysis (Part 1)

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  • Henry Glick

Abstract

Basic sample size and power formulae for cost-effectiveness analysis have been established in the literature. These formulae are reviewed and the similarities and differences between sample size and power for cost-effectiveness analysis and for the analysis of other continuous variables such as changes in blood pressure or weight are described. The types of sample size and power tables that are commonly calculated for cost-effectiveness analysis are also described and the impact of varying the assumed parameter values on the resulting sample size and power estimates is discussed. Finally, the way in which the data for these calculations may be derived are discussed. Copyright Springer International Publishing AG 2011

Suggested Citation

  • Henry Glick, 2011. "Sample Size and Power for Cost-Effectiveness Analysis (Part 1)," PharmacoEconomics, Springer, vol. 29(3), pages 189-198, March.
    • Handle: RePEc:spr:pharme:v:29:y:2011:i:3:p:189-198
    DOI: 10.2165/11585070-000000000-00000
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    References listed on IDEAS

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    8. Andrew H. Briggs & Alastair M. Gray, 1998. "Power and Sample Size Calculations for Stochastic Cost-Effectiveness Analysis," Medical Decision Making, , vol. 18(2_suppl), pages 81-92, April.
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    10. Glick, Henry A & Doshi, Jalpa A & Sonnad, Seema S & Polsky, Daniel, 2007. "Economic Evaluation in Clinical Trials," OUP Catalogue, Oxford University Press, number 9780198529972.
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