IDEAS home Printed from https://ideas.repec.org/a/sae/medema/v18y1998i2_supplps81-s92.html
   My bibliography  Save this article

Power and Sample Size Calculations for Stochastic Cost-Effectiveness Analysis

Author

Listed:
  • Andrew H. Briggs
  • Alastair M. Gray

Abstract

As the data for economic analyses are increasingly collected prospectively alongside clinical trials, many commentators have highlighted that the sample sizes in such trials should be based on the requirements for the economic analysis as well as those for the clinical evaluation. However, issues associated with sample size calculations for economic analysis have yet to receive the rigorous attention given to sample size calculation for clinical evaluation. In particular, no sample size formula for cost-ef fectiveness analysis is available for analysts hoping either to calculate the required sample size at the design stage of a study or to calculate the power a given size of clinical trial will generate for cost-effectiveness analysis. Building on the recent liter ature for calculating confidence intervals for cost-effectiveness ratios, the authors ex plore possible techniques for deriving a sample size formula for cost-effectiveness analysis based on simple combination of the confidence limits on costs and effects. Key words: cost-effectiveness; economic analysis; sample size; methodology. (Med Decis Making 1998;18 suppl:S81-S92)

Suggested Citation

  • Andrew H. Briggs & Alastair M. Gray, 1998. "Power and Sample Size Calculations for Stochastic Cost-Effectiveness Analysis," Medical Decision Making, , vol. 18(2_suppl), pages 81-92, April.
    • Handle: RePEc:sae:medema:v:18:y:1998:i:2_suppl:p:s81-s92
    DOI: 10.1177/0272989X98018002S10
    as

    Download full text from publisher

    File URL: https://journals.sagepub.com/doi/10.1177/0272989X98018002S10
    Download Restriction: no
    File URL: https://libkey.io/10.1177/0272989X98018002S10?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Andrew Briggs & Mark Sculpher & Martin Buxton, 1994. "Uncertainty in the economic evaluation of health care technologies: The role of sensitivity analysis," Health Economics, John Wiley & Sons, Ltd., vol. 3(2), pages 95-104, March.
    2. Jack Dowie, 1997. "Clinical Trials and Economic Evaluations? No, There are Only Evaluations," Health Economics, John Wiley & Sons, Ltd., vol. 6(1), pages 87-89, January.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Henry Glick, 2011. "Sample Size and Power for Cost-Effectiveness Analysis (Part 1)," PharmacoEconomics, Springer, vol. 29(3), pages 189-198, March.
    2. A. Gafni & S. D. Walter & S. Birch & P. Sendi, 2008. "An opportunity cost approach to sample size calculation in cost‐effectiveness analysis," Health Economics, John Wiley & Sons, Ltd., vol. 17(1), pages 99-107, January.
    3. Gafni, Amiram & Birch, Stephen, 2006. "Incremental cost-effectiveness ratios (ICERs): The silence of the lambda," Social Science & Medicine, Elsevier, vol. 62(9), pages 2091-2100, May.
    4. Niklas Zethraeus & Magnus Johannesson & Bengt Jönsson & Mickael Löthgren & Magnus Tambour, 2003. "Advantages of Using the Net-Benefit Approach for Analysing Uncertainty in Economic Evaluation Studies," PharmacoEconomics, Springer, vol. 21(1), pages 39-48, January.
    5. Andrew R. Willan & Bernie J. O'Brien, 1999. "Sample size and power issues in estimating incremental cost‐effectiveness ratios from clinical trials data," Health Economics, John Wiley & Sons, Ltd., vol. 8(3), pages 203-211, May.
    6. Kobelt, G., 2013. "Health Economics: An Introduction to Economic Evaluation," Monographs, Office of Health Economics, number 000004.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. John Hutton, 2012. "‘Health Economics’ and the evolution of economic evaluation of health technologies," Health Economics, John Wiley & Sons, Ltd., vol. 21(1), pages 13-18, January.
    2. Martin J. Buxton & Michael F. Drummond & Ben A. Van Hout & Richard L. Prince & Trevor A. Sheldon & Thomas Szucs & Muriel Vray, 1997. "Modelling in Ecomomic Evaluation: An Unavoidable Fact of Life," Health Economics, John Wiley & Sons, Ltd., vol. 6(3), pages 217-227, May.
    3. Isaac Corro Ramos & Maureen P. M. H. Rutten-van Mölken & Maiwenn J. Al, 2013. "The Role of Value-of-Information Analysis in a Health Care Research Priority Setting," Medical Decision Making, , vol. 33(4), pages 472-489, May.
    4. Gianluca Baio & Laura Magazzini & Claudia Oglialoro & Fabio Pammolli & Massimo Riccaboni, 2005. "Medical Devices: Competitiveness and Impact on Public Health Expenditure," Working Papers CERM 05-2005, Competitività, Regole, Mercati (CERM).
    5. K Cooper & S C Brailsford & R Davies, 2007. "Choice of modelling technique for evaluating health care interventions," Journal of the Operational Research Society, Palgrave Macmillan;The OR Society, vol. 58(2), pages 168-176, February.
    6. Berger, Loïc & Bleichrodt, Han & Eeckhoudt, Louis, 2013. "Treatment decisions under ambiguity," Journal of Health Economics, Elsevier, vol. 32(3), pages 559-569.
    7. Matthew Franklin & James Lomas & Simon Walker & Tracey Young, 2019. "An Educational Review About Using Cost Data for the Purpose of Cost-Effectiveness Analysis," PharmacoEconomics, Springer, vol. 37(5), pages 631-643, May.
    8. Kaan Sözmen & Belgin Unal & Simon Capewell & Julia Critchley & Martin O’Flaherty, 2015. "Estimating diabetes prevalence in Turkey in 2025 with and without possible interventions to reduce obesity and smoking prevalence, using a modelling approach," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 60(1), pages 13-21, January.
    9. Sebastian Gurtner, 2013. "An analysis of the influence of framework aspects on the study design of health economic modeling evaluations," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 14(2), pages 221-230, April.
    10. Nancy Wolff & Thomas W. Helminiak, 1996. "Nonsampling measurement error in administrative data: Implications for economic evaluations," Health Economics, John Wiley & Sons, Ltd., vol. 5(6), pages 501-512, November.
    11. Kobelt, G., 2013. "Health Economics: An Introduction to Economic Evaluation," Monographs, Office of Health Economics, number 000004.
    12. Baines, Darrin & Disegna, Marta & Hartwell, Christopher A., 2021. "Portfolio frontier analysis: Applying mean-variance analysis to health technology assessment for health systems under pressure," Social Science & Medicine, Elsevier, vol. 276(C).
    13. James C. Felli & Gordon B. Hazen, 1999. "A Bayesian approach to sensitivity analysis," Health Economics, John Wiley & Sons, Ltd., vol. 8(3), pages 263-268, May.
    14. Hendriek Boshuizen & Stefan Lhachimi & Pieter Baal & Rudolf Hoogenveen & Henriette Smit & Johan Mackenbach & Wilma Nusselder, 2012. "The DYNAMO-HIA Model: An Efficient Implementation of a Risk Factor/Chronic Disease Markov Model for Use in Health Impact Assessment (HIA)," Demography, Springer;Population Association of America (PAA), vol. 49(4), pages 1259-1283, November.
    15. Meredith Wilcox & Helen Mason & Fouad Fouad & Samer Rastam & Radwan Ali & Timothy Page & Simon Capewell & Martin O’Flaherty & Wasim Maziak, 2015. "Cost-effectiveness analysis of salt reduction policies to reduce coronary heart disease in Syria, 2010–2020," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 60(1), pages 23-30, January.
    16. Paula K Lorgelly, 2018. "The Impact of Brexit on Pharmaceuticals and HTA," PharmacoEconomics - Open, Springer, vol. 2(2), pages 87-91, June.
    17. Stephen Palmer & Peter Smith, 1999. "Incorporating option values into the economic evaluation of health care technologies," Working Papers 166chedp, Centre for Health Economics, University of York.
    18. John Paul Ekwaru & Arto Ohinmaa & Bach Xuan Tran & Solmaz Setayeshgar & Jeffrey A Johnson & Paul J Veugelers, 2017. "Cost-effectiveness of a school-based health promotion program in Canada: A life-course modeling approach," PLOS ONE, Public Library of Science, vol. 12(5), pages 1-13, May.
    19. Joseph N Jarvis & Thomas S Harrison & Stephen D Lawn & Graeme Meintjes & Robin Wood & Susan Cleary, 2013. "Cost Effectiveness of Cryptococcal Antigen Screening as a Strategy to Prevent HIV-Associated Cryptococcal Meningitis in South Africa," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-9, July.
    20. Yesim Tozan & Sicong Sun & Ariadna Capasso & Julia Shu-Huah Wang & Torsten B Neilands & Ozge Sensoy Bahar & Christopher Damulira & Fred M Ssewamala, 2019. "Evaluation of a savings-led family-based economic empowerment intervention for AIDS-affected adolescents in Uganda: A four-year follow-up on efficacy and cost-effectiveness," PLOS ONE, Public Library of Science, vol. 14(12), pages 1-13, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:sae:medema:v:18:y:1998:i:2_suppl:p:s81-s92. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: SAGE Publications (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.