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A Review of the Costs and Cost Effectiveness of Interventions in Chronic Kidney Disease

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Listed:
  • Joseph Menzin
  • Lisa Lines
  • Daniel Weiner
  • Peter Neumann
  • Christine Nichols
  • Lauren Rodriguez
  • Irene Agodoa
  • Tracy Mayne

Abstract

Given rising healthcare costs and a growing population of patients with chronic kidney disease (CKD), there is an urgent need to identify health interventions that provide good value for money. For this review, the English-language literature was searched for studies of interventions in CKD reporting an original incremental cost-utility (cost per QALY) or cost-effectiveness (cost per life-year) ratio. Published cost studies that did not report cost-effectiveness or cost-utility ratios were also reviewed. League tables were then created for both cost-utility and cost-effectiveness ratios to assess interventions in patients with stage 1–4 CKD, waitlist and transplant patients and those with end-stage renal disease (ESRD). In addition, the percentage of cost-saving or dominant interventions (those that save money and improve health) was compared across these three disease categories. A total of 84 studies were included, contributing 72 cost-utility ratios, 20 cost-effectiveness ratios and 42 other cost measures. Many of the interventions were dominant over the comparator, indicating better health outcomes and lower costs. For the three disease categories, the greatest number of dominant or cost-saving interventions was reported for stage 14 CKD patients, followed by waitlist and transplant recipients and those with ESRD (91%, 87% and 55% of studies reporting a dominant or cost-saving intervention, respectively). There is evidence of opportunities to lower costs in the treatment of patients with CKD, while either improving or maintaining the quality of care. In order to realize these cost savings, efforts will be required to promote and effectively implement changes in treatment practices. Copyright Adis Data Information BV 2011

Suggested Citation

  • Joseph Menzin & Lisa Lines & Daniel Weiner & Peter Neumann & Christine Nichols & Lauren Rodriguez & Irene Agodoa & Tracy Mayne, 2011. "A Review of the Costs and Cost Effectiveness of Interventions in Chronic Kidney Disease," PharmacoEconomics, Springer, vol. 29(10), pages 839-861, October.
  • Handle: RePEc:spr:pharme:v:29:y:2011:i:10:p:839-861
    DOI: 10.2165/11588390-000000000-00000
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    References listed on IDEAS

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    1. Chris P. Lee & Glenn M. Chertow & Stefanos A. Zenios, 2006. "A Simulation Model to Estimate the Cost and Effectiveness of Alternative Dialysis Initiation Strategies," Medical Decision Making, , vol. 26(5), pages 535-549, September.
    2. Andrew Palmer & William Valentine & Joshua Ray & Stephane Roze & Noemi Muszbek, 2007. "Health economic implications of irbesartan treatment versus standard blood pressure control in patients with type 2 diabetes, hypertension and renal disease: a Hungarian analysis," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 8(2), pages 161-168, June.
    3. Ivy Chow & Elkin Lemos & Thomas Einarson, 2008. "Management and Prevention of Diabetic Foot Ulcers and Infections," PharmacoEconomics, Springer, vol. 26(12), pages 1019-1035, December.
    4. Kontodimopoulos, Nick & Niakas, Dimitris, 2008. "An estimate of lifelong costs and QALYs in renal replacement therapy based on patients' life expectancy," Health Policy, Elsevier, vol. 86(1), pages 85-96, April.
    5. Braden Manns & David Meltzer & Ken Taub & Cam Donaldson, 2003. "Illustrating the impact of including future costs in economic evaluations: an application to end‐stage renal disease care," Health Economics, John Wiley & Sons, Ltd., vol. 12(11), pages 949-958, November.
    6. de Wit, G.Ardine & Ramsteijn, Paul G & de Charro, Frank Th, 1998. "Economic evaluation of end stage renal disease treatment," Health Policy, Elsevier, vol. 44(3), pages 215-232, June.
    7. George Carides & Shahnaz Shahinfar & Erik Dasbach & William Keane & William Gerth & Charles Alexander & William Herman & Barry Brenner, 2006. "The Impact of Losartan on the Lifetime Incidence of End-Stage Renal Disease and Costs in Patients with Type 2 Diabetes and Nephropathy," PharmacoEconomics, Springer, vol. 24(6), pages 549-558, June.
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