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Joint analysis of interval-censored failure time data and panel count data

Author

Listed:
  • Da Xu

    (Jilin University)

  • Hui Zhao

    (Central China Normal University)

  • Jianguo Sun

    (Jilin University
    University of Missouri)

Abstract

Interval-censored failure time data and panel count data are two types of incomplete data that commonly occur in event history studies and many methods have been developed for their analysis separately (Sun in The statistical analysis of interval-censored failure time data. Springer, New York, 2006; Sun and Zhao in The statistical analysis of panel count data. Springer, New York, 2013). Sometimes one may be interested in or need to conduct their joint analysis such as in the clinical trials with composite endpoints, for which it does not seem to exist an established approach in the literature. In this paper, a sieve maximum likelihood approach is developed for the joint analysis and in the proposed method, Bernstein polynomials are used to approximate unknown functions. The asymptotic properties of the resulting estimators are established and in particular, the proposed estimators of regression parameters are shown to be semiparametrically efficient. In addition, an extensive simulation study was conducted and the proposed method is applied to a set of real data arising from a skin cancer study.

Suggested Citation

  • Da Xu & Hui Zhao & Jianguo Sun, 2018. "Joint analysis of interval-censored failure time data and panel count data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 24(1), pages 94-109, January.
    • Handle: RePEc:spr:lifeda:v:24:y:2018:i:1:d:10.1007_s10985-017-9397-0
    DOI: 10.1007/s10985-017-9397-0
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    References listed on IDEAS

    as
    1. Bodhisattva Sen & Moulinath Banerjee, 2007. "A pseudolikelihood method for analyzing interval censored data," Biometrika, Biometrika Trust, vol. 94(1), pages 71-86.
    2. Lu, Minggen & Zhang, Ying & Huang, Jian, 2009. "Semiparametric Estimation Methods for Panel Count Data Using Monotone B-Splines," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1060-1070.
    3. Osman, Muhtarjan & Ghosh, Sujit K., 2012. "Nonparametric regression models for right-censored data using Bernstein polynomials," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 559-573.
    4. Ying Zhang & Lei Hua & Jian Huang, 2010. "A Spline‐Based Semiparametric Maximum Likelihood Estimation Method for the Cox Model with Interval‐Censored Data," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 37(2), pages 338-354, June.
    5. Ling Ma & Tao Hu & Jianguo Sun, 2015. "Sieve maximum likelihood regression analysis of dependent current status data," Biometrika, Biometrika Trust, vol. 102(3), pages 731-738.
    6. J. Sun & L. J. Wei, 2000. "Regression analysis of panel count data with covariate‐dependent observation and censoring times," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 62(2), pages 293-302.
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    Cited by:

    1. Douglas E. Schaubel & Bin Nan, 2018. "Special issue dedicated to Jack Kalbfleisch," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 24(1), pages 1-2, January.

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