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Semiparametric regression analysis of panel count data allowing for within-subject correlation

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  • Yao, Bin
  • Wang, Lianming
  • He, Xin

Abstract

In this paper, a maximum likelihood approach is proposed for analyzing panel count data under the gamma frailty non-homogeneous Poisson process model. The approach allows one to estimate the baseline mean function and the regression parameters jointly while taking the within-subject correlation into account. The within-subject correlation is quantified explicitly by Pearson’s correlation coefficient. Monotone splines are adopted to approximate the unspecified nondecreasing baseline mean function in the model. An expectation–maximization (EM) algorithm is derived to facilitate the computation by exploiting a data augmentation based on Poisson latent variables. The EM algorithm is robust to initial values, easy to implement, converges fast, and provides closed-form variance estimates. It can be also applied to the non-homogeneous Poisson model without frailty. The proposed approach is evaluated through simulations and illustrated by two real-life examples coming from a skin cancer study and a bladder tumor study. A companion R package PCDSpline has been developed and is available on R CRAN for public use.

Suggested Citation

  • Yao, Bin & Wang, Lianming & He, Xin, 2016. "Semiparametric regression analysis of panel count data allowing for within-subject correlation," Computational Statistics & Data Analysis, Elsevier, vol. 97(C), pages 47-59.
    • Handle: RePEc:eee:csdana:v:97:y:2016:i:c:p:47-59
    DOI: 10.1016/j.csda.2015.11.017
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    References listed on IDEAS

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    1. Jianguo Sun, 2003. "A nonparametric test for panel count data," Biometrika, Biometrika Trust, vol. 90(1), pages 199-208, March.
    2. Ying Zhang & Mortaza Jamshidian, 2003. "The Gamma-Frailty Poisson Model for the Nonparametric Estimation of Panel Count Data," Biometrics, The International Biometric Society, vol. 59(4), pages 1099-1106, December.
    3. Cai, Bo & Lin, Xiaoyan & Wang, Lianming, 2011. "Bayesian proportional hazards model for current status data with monotone splines," Computational Statistics & Data Analysis, Elsevier, vol. 55(9), pages 2644-2651, September.
    4. Lu, Minggen & Zhang, Ying & Huang, Jian, 2009. "Semiparametric Estimation Methods for Panel Count Data Using Monotone B-Splines," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1060-1070.
    5. Lianming Wang & David B. Dunson, 2011. "Semiparametric Bayes' Proportional Odds Models for Current Status Data with Underreporting," Biometrics, The International Biometric Society, vol. 67(3), pages 1111-1118, September.
    6. Ying Zhang, 2002. "A semiparametric pseudolikelihood estimation method for panel count data," Biometrika, Biometrika Trust, vol. 89(1), pages 39-48, March.
    7. Ying Zhang, 2006. "Nonparametric k-sample tests with panel count data," Biometrika, Biometrika Trust, vol. 93(4), pages 777-790, December.
    8. Zhang, Haixiang & Zhao, Hui & Sun, Jianguo & Wang, Dehui & Kim, KyungMann, 2013. "Regression analysis of multivariate panel count data with an informative observation process," Journal of Multivariate Analysis, Elsevier, vol. 119(C), pages 71-80.
    9. Minggen Lu & Ying Zhang & Jian Huang, 2007. "Estimation of the mean function with panel count data using monotone polynomial splines," Biometrika, Biometrika Trust, vol. 94(3), pages 705-718.
    10. X. Joan Hu & Jianguo Sun & Lee‐Jen Wei, 2003. "Regression Parameter Estimation from Panel Counts," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 30(1), pages 25-43, March.
    11. Li, Yang & Zhao, Hui & Sun, Jianguo & Kim, KyungMann, 2014. "Nonparametric tests for panel count data with unequal observation processes," Computational Statistics & Data Analysis, Elsevier, vol. 73(C), pages 103-111.
    12. Zhao, Xingqiu & Tong, Xingwei & Sun, Jianguo, 2013. "Robust estimation for panel count data with informative observation times," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 33-40.
    13. J. Sun & L. J. Wei, 2000. "Regression analysis of panel count data with covariate‐dependent observation and censoring times," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 62(2), pages 293-302.
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    Cited by:

    1. John D. Rice & Robert L. Strawderman & Brent A. Johnson, 2018. "Regularity of a renewal process estimated from binary data," Biometrics, The International Biometric Society, vol. 74(2), pages 566-574, June.

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