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Multidimensional Assessment of Subjective Well-being and Risk of Dementia: Findings from the UK Biobank Study

Author

Listed:
  • Xianghe Zhu

    (Florida State University
    Wenzhou Medical University)

  • Martina Luchetti

    (Florida State University)

  • Damaris Aschwanden

    (Florida State University)

  • Amanda A. Sesker

    (Florida State University)

  • Yannick Stephan

    (University of Montpellier)

  • Angelina R. Sutin

    (Florida State University)

  • Antonio Terracciano

    (Florida State University)

Abstract

This study aimed to examine the associations between subjective well-being (SWB) and risk of all-cause dementia, Alzheimer’s disease (AD), and vascular dementia (VD). We adopted a multidimensional approach to SWB that included the level and breadth of SWB, the latter indicating the extent to which SWB spreads across life domains. Participants (N = 171,197; mean age = 56.78; SD = 8.16 years) were part of the UK Biobank and were followed up to 8.78 years. Domain-general and domain-specific SWB were measured by single items, and the breadth of SWB was indexed with a cumulative score of satisfaction across domains. Dementia incidence was ascertained through hospital and death records. Cox regression was used to examine the association between SWB indicators and risk of all-cause dementia, AD, and VD. General happiness, health and family satisfaction, and satisfaction breadth (satisfaction in multiple domains) were associated with lower risk of all-cause dementia. The associations held after accounting for socio-demographics, health, behavioral, and economic covariates, and depressive symptoms. Health satisfaction and the breadth of satisfaction were also associated with lower risk of AD and VD, with a pattern of slightly stronger associations for VD compared to AD. Some life domains (e.g., health) may be more fruitfully targeted to promote well-being and help protect against dementia, but it is also important to enhance well-being across multiple domains to maximize the protective effects.

Suggested Citation

  • Xianghe Zhu & Martina Luchetti & Damaris Aschwanden & Amanda A. Sesker & Yannick Stephan & Angelina R. Sutin & Antonio Terracciano, 2023. "Multidimensional Assessment of Subjective Well-being and Risk of Dementia: Findings from the UK Biobank Study," Journal of Happiness Studies, Springer, vol. 24(2), pages 629-650, February.
    • Handle: RePEc:spr:jhappi:v:24:y:2023:i:2:d:10.1007_s10902-022-00613-3
    DOI: 10.1007/s10902-022-00613-3
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    References listed on IDEAS

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