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Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life

Author

Listed:
  • Caterina Alacevich

    (University of Oxford
    University of Florida)

  • Inna Thalmann

    (University of Oxford)

  • Catia Nicodemo

    (University of Oxford
    Department of Economics, University of Verona)

  • Simon Lusignan

    (University of Oxford)

  • Stavros Petrou

    (University of Oxford)

Abstract

Background Understanding the physical and mental health needs of the population through evidence-based research is a priority for informing health policy. During the COVID-19 pandemic, population wellbeing dramatically dropped. The relationship between experiences of symptomatic illness episodes and health-related quality of life has been less documented. Objective This study analysed the association between symptomatic COVID-19 illness and health-related quality of life. Methods The analyses drew from a cross-sectional analysis of data from a national digital symptoms’ surveillance survey conducted in the UK in 2020. We identified illness episodes using symptoms and test results data and we analysed validated health-related quality of life outcomes including health utility scores (indexed on a 0–1 cardinal scale) and visual analogue scale (VAS) scores (0–100 scale) generated by the EuroQoL’s EQ-5D-5L measure. The econometric model controlled for respondents’ demographic and socioeconomic characteristics, comorbidities, social isolation measures, and regional and time fixed effects. Results The results showed that the experience of common SARS-CoV-2 symptoms was significantly associated with poorer health-related quality of life across all EQ-5D-5L dimensions of mobility, self-care, usual activities, pain/discomfort and anxiety/depression, a decrement in utility score of − 0.13 and a decrement in the EQ-VAS score of − 15. The findings were robust to sensitivity analyses and restrictive test results-based definitions. Conclusion This evidence-based study highlights the need for targeting of interventions and services towards those experiencing symptomatic episodes during future waves of the pandemic and helps to quantify the benefits of SARS-CoV-2 treatment in terms of health-related quality of life.

Suggested Citation

  • Caterina Alacevich & Inna Thalmann & Catia Nicodemo & Simon Lusignan & Stavros Petrou, 2023. "Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life," Applied Health Economics and Health Policy, Springer, vol. 21(5), pages 761-771, September.
    • Handle: RePEc:spr:aphecp:v:21:y:2023:i:5:d:10.1007_s40258-023-00810-y
    DOI: 10.1007/s40258-023-00810-y
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    References listed on IDEAS

    as
    1. Michael C Grant & Luke Geoghegan & Marc Arbyn & Zakaria Mohammed & Luke McGuinness & Emily L Clarke & Ryckie G Wade, 2020. "The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-19, June.
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    More about this item

    JEL classification:

    • C1 - Mathematical and Quantitative Methods - - Econometric and Statistical Methods and Methodology: General
    • I1 - Health, Education, and Welfare - - Health
    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • I31 - Health, Education, and Welfare - - Welfare, Well-Being, and Poverty - - - General Welfare, Well-Being

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