IDEAS home Printed from https://ideas.repec.org/a/spr/aistmt/v73y2021i2d10.1007_s10463-020-00752-5.html
   My bibliography  Save this article

On the power of some sequential multiple testing procedures

Author

Listed:
  • Shiyun Chen

    (Amazon)

  • Ery Arias-Castro

    (University of California)

Abstract

We study an online multiple testing problem where the hypotheses arrive sequentially in a stream. The test statistics are independent and assumed to have the same distribution under their respective null hypotheses. We investigate two recently proposed procedures LORD and LOND, which are proved to control the FDR in an online manner. In some (static) model, we show that LORD is optimal in some asymptotic sense, in particular as powerful as the (static) Benjamini–Hochberg procedure to first asymptotic order. We also quantify the performance of LOND. Some numerical experiments complement our theory.

Suggested Citation

  • Shiyun Chen & Ery Arias-Castro, 2021. "On the power of some sequential multiple testing procedures," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 73(2), pages 311-336, April.
    • Handle: RePEc:spr:aistmt:v:73:y:2021:i:2:d:10.1007_s10463-020-00752-5
    DOI: 10.1007/s10463-020-00752-5
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s10463-020-00752-5
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s10463-020-00752-5?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Ehud Aharoni & Saharon Rosset, 2014. "Generalized α-investing: definitions, optimality results and application to public databases," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 76(4), pages 771-794, September.
    2. Sun, Wenguang & Cai, T. Tony, 2007. "Oracle and Adaptive Compound Decision Rules for False Discovery Rate Control," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 901-912, September.
    3. Ang Li & Rina Foygel Barber, 2017. "Accumulation Tests for FDR Control in Ordered Hypothesis Testing," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(518), pages 837-849, April.
    4. Max Grazier G'Sell & Stefan Wager & Alexandra Chouldechova & Robert Tibshirani, 2016. "Sequential selection procedures and false discovery rate control," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 78(2), pages 423-444, March.
    5. John D. Storey, 2007. "The optimal discovery procedure: a new approach to simultaneous significance testing," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 69(3), pages 347-368, June.
    6. Christopher Genovese & Larry Wasserman, 2002. "Operating characteristics and extensions of the false discovery rate procedure," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(3), pages 499-517, August.
    7. John D. Storey, 2002. "A direct approach to false discovery rates," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(3), pages 479-498, August.
    8. Dean P. Foster & Robert A. Stine, 2008. "α‐investing: a procedure for sequential control of expected false discoveries," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 70(2), pages 429-444, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wenguang Sun & T. Tony Cai, 2009. "Large‐scale multiple testing under dependence," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 71(2), pages 393-424, April.
    2. Gong, Siliang & Zhang, Kai & Liu, Yufeng, 2018. "Efficient test-based variable selection for high-dimensional linear models," Journal of Multivariate Analysis, Elsevier, vol. 166(C), pages 17-31.
    3. Cipolli III, William & Hanson, Timothy & McLain, Alexander C., 2016. "Bayesian nonparametric multiple testing," Computational Statistics & Data Analysis, Elsevier, vol. 101(C), pages 64-79.
    4. T. Tony Cai & Wenguang Sun & Weinan Wang, 2019. "Covariate‐assisted ranking and screening for large‐scale two‐sample inference," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 81(2), pages 187-234, April.
    5. Saharon Rosset & Ruth Heller & Amichai Painsky & Ehud Aharoni, 2022. "Optimal and maximin procedures for multiple testing problems," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 84(4), pages 1105-1128, September.
    6. Jeng, X. Jessie & Chen, Xiongzhi, 2019. "Predictor ranking and false discovery proportion control in high-dimensional regression," Journal of Multivariate Analysis, Elsevier, vol. 171(C), pages 163-175.
    7. Habiger, Joshua D. & Peña, Edsel A., 2014. "Compound p-value statistics for multiple testing procedures," Journal of Multivariate Analysis, Elsevier, vol. 126(C), pages 153-166.
    8. Ruth Heller & Saharon Rosset, 2021. "Optimal control of false discovery criteria in the two‐group model," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 83(1), pages 133-155, February.
    9. Xiaoquan Wen, 2017. "Robust Bayesian FDR Control Using Bayes Factors, with Applications to Multi-tissue eQTL Discovery," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 9(1), pages 28-49, June.
    10. Izmirlian, Grant, 2020. "Strong consistency and asymptotic normality for quantities related to the Benjamini–Hochberg false discovery rate procedure," Statistics & Probability Letters, Elsevier, vol. 160(C).
    11. T. Tony Cai & Wenguang Sun, 2017. "Optimal screening and discovery of sparse signals with applications to multistage high throughput studies," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 79(1), pages 197-223, January.
    12. Jiaying Gu & Roger Koenker, 2020. "Invidious Comparisons: Ranking and Selection as Compound Decisions," Papers 2012.12550, arXiv.org, revised Sep 2021.
    13. Pengfei Wang & Wensheng Zhu, 2022. "Large‐scale covariate‐assisted two‐sample inference under dependence," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 49(4), pages 1421-1447, December.
    14. Cai, Qingyun, 2018. "A scoring criterion for rejection of clustered p-values," Computational Statistics & Data Analysis, Elsevier, vol. 121(C), pages 180-189.
    15. Jiaying Gu & Roger Koenker, 2023. "Invidious Comparisons: Ranking and Selection as Compound Decisions," Econometrica, Econometric Society, vol. 91(1), pages 1-41, January.
    16. Tingting Cui & Pengfei Wang & Wensheng Zhu, 2021. "Covariate-adjusted multiple testing in genome-wide association studies via factorial hidden Markov models," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 30(3), pages 737-757, September.
    17. B. Moerkerke & E. Goetghebeur & J. De Riek & I. Roldán‐Ruiz, 2006. "Significance and impotence: towards a balanced view of the null and the alternative hypotheses in marker selection for plant breeding," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 169(1), pages 61-79, January.
    18. Daniel Yekutieli, 2015. "Bayesian tests for composite alternative hypotheses in cross-tabulated data," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 24(2), pages 287-301, June.
    19. Gómez-Villegas Miguel A. & Salazar Isabel & Sanz Luis, 2014. "A Bayesian decision procedure for testing multiple hypotheses in DNA microarray experiments," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 13(1), pages 49-65, February.
    20. Long Qu & Dan Nettleton & Jack C. M. Dekkers, 2012. "Improved Estimation of the Noncentrality Parameter Distribution from a Large Number of t-Statistics, with Applications to False Discovery Rate Estimation in Microarray Data Analysis," Biometrics, The International Biometric Society, vol. 68(4), pages 1178-1187, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:aistmt:v:73:y:2021:i:2:d:10.1007_s10463-020-00752-5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.