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Health State Utilities in Gastroesophageal Reflux Disease Patients with Heartburn: A Study in Germany and Sweden

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  • Bernt Kartman
  • Gudrun Gatz
  • Magnus Johannesson

Abstract

The objectives of this study were to assess health state utilities in patients with gastroesophageal reflux disease with heartburn and to analyze if severity and annual frequency of heartburn can predict utilities. Atotal of 1011 patients in Germany and Sweden participated in telephone interviews, where utilities were assessed using the rating scale (RS), EQ-5D, time trade-off (TTO) and standard gamble (SG) instruments. The average RS, EQ-5D, TTO, and SG utilities were 0.69, 0.70, 0.88, and 0.89, respectively. Linear regression analyses showed that the EQ-5D and RS utilities were negativelyand significantly related to the severity and frequency of heartburn. The EQ-5D and RS results indicate that patients with heartburn assign their health states substantial disutility and that it is feasible to estimate regression equations to predict utilities from heartburn-specific variables. In the TTO and SGanalyses, the impact of heartburnwas in the expected direction but smaller and in general not significant.

Suggested Citation

  • Bernt Kartman & Gudrun Gatz & Magnus Johannesson, 2004. "Health State Utilities in Gastroesophageal Reflux Disease Patients with Heartburn: A Study in Germany and Sweden," Medical Decision Making, , vol. 24(1), pages 40-52, January.
    • Handle: RePEc:sae:medema:v:24:y:2004:i:1:p:40-52
    DOI: 10.1177/027298X03261563
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    References listed on IDEAS

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    1. Paul Dolan & Claire Gudex & Paul Kind & Alan Williams, 1996. "The time trade‐off method: Results from a general population study," Health Economics, John Wiley & Sons, Ltd., vol. 5(2), pages 141-154, March.
    2. Torrance, George W., 1986. "Measurement of health state utilities for economic appraisal : A review," Journal of Health Economics, Elsevier, vol. 5(1), pages 1-30, March.
    3. Isaac M. Lipkus & Greg Samsa & Barbara K. Rimer, 2001. "General Performance on a Numeracy Scale among Highly Educated Samples," Medical Decision Making, , vol. 21(1), pages 37-44, February.
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    1. Kristina Boye & Louis Matza & Kimberly Walter & Kate Brunt & Andrew Palsgrove & Aodan Tynan, 2011. "Utilities and disutilities for attributes of injectable treatments for type 2 diabetes," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 12(3), pages 219-230, June.

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