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Economic Evaluation of Vaccination Programs: The Impact of Herd-Immunity

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  • M. Brisson
  • W. J. Edmunds

Abstract

The unique characteristic of vaccination is that it not only reduces the incidence of disease in those immunized but also indirectly protects nonvaccinated susceptibles against infection (produces herd-immunity). The bulk of economic evaluations of vaccination programs continue to use models that cannot take into account the indirect effects produced by herd-immunity. Here, the authors illustrate the importance of incorporating herd-immunity externalities when assessing the cost-effectiveness of vaccination programs. To do this, they compare 2 methods of estimating the benefits of routine mass vaccination: one that includes herd-immunity (dynamic approach) and one that does not (static approach). Finally, they use the results to clarify a number of misconceptions that are common in the literature concerning herd immunity and dynamical effects produced by models.

Suggested Citation

  • M. Brisson & W. J. Edmunds, 2003. "Economic Evaluation of Vaccination Programs: The Impact of Herd-Immunity," Medical Decision Making, , vol. 23(1), pages 76-82, January.
    • Handle: RePEc:sae:medema:v:23:y:2003:i:1:p:76-82
    DOI: 10.1177/0272989X02239651
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    Citations

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    Cited by:

    1. Sang-Man Kim & Arben Asllani, 2013. "Using simulation to establish appropriate vaccination rates and copayment policies from a cost perspective," Service Business, Springer;Pan-Pacific Business Association, vol. 7(3), pages 437-457, September.
    2. Caroline L. Trotter & W. John Edmunds, 2006. "Reassessing the Cost-Effectiveness of Meningococcal Serogroup C Conjugate (MCC) Vaccines Using a Transmission Dynamic Model," Medical Decision Making, , vol. 26(1), pages 38-47, January.
    3. Greg Plosker, 2011. "Rotavirus Vaccine RIX4414 (Rotarix™)," PharmacoEconomics, Springer, vol. 29(11), pages 989-1009, November.
    4. Andrea Anonychuk & Andrea Tricco & Chris Bauch & Ba’ Pham & Vladimir Gilca & Bernard Duval & Ava John-Baptiste & Gloria Woo & Murray Krahn, 2008. "Cost-Effectiveness Analyses of Hepatitis A Vaccine," PharmacoEconomics, Springer, vol. 26(1), pages 17-32, January.
    5. Radboud J. Duintjer Tebbens & Kimberly M. Thompson, 2009. "Priority Shifting and the Dynamics of Managing Eradicable Infectious Diseases," Management Science, INFORMS, vol. 55(4), pages 650-663, April.
    6. Wang, Qingqing & Du, Chunpeng & Geng, Yini & Shi, Lei, 2020. "Historical payoff can not overcome the vaccination dilemma on Barabási–Albert scale-free networks," Chaos, Solitons & Fractals, Elsevier, vol. 130(C).
    7. Arnold Kamis & Yuji Zhang & Tamara Kamis, 2017. "A Multiyear Model of Influenza Vaccination in the United States," IJERPH, MDPI, vol. 14(8), pages 1-14, July.
    8. Choudhury, Agnitra Roy & Polachek, Solomon, 2019. "The Impact of Paid Family Leave on the Timing of Infant Vaccinations," IZA Discussion Papers 12483, Institute of Labor Economics (IZA).
    9. Iwamura, Yoshiro & Tanimoto, Jun, 2018. "Realistic decision-making processes in a vaccination game," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 494(C), pages 236-241.
    10. Rachel Elliott & Helen Weatherly & Neil Hawkins & Gillian Cranny & Duncan Chambers & Lindsey Myers & Alison Eastwood & Mark Sculpher, 2010. "An economic model for the prevention of MRSA infections after surgery: non-glycopeptide or glycopeptide antibiotic prophylaxis?," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 11(1), pages 57-66, February.
    11. Wang, Jianwei & Xu, Wenshu & Chen, Wei & Yu, Fengyuan & He, Jialu, 2021. "Information sharing can suppress the spread of epidemics: Voluntary vaccination game on two-layer networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 583(C).
    12. Mario Songane, 2018. "Challenges for nationwide vaccine delivery in African countries," International Journal of Health Economics and Management, Springer, vol. 18(2), pages 197-219, June.
    13. Anna K. Lugnér & Sido D. Mylius & Jacco Wallinga, 2010. "Dynamic versus static models in cost‐effectiveness analyses of anti‐viral drug therapy to mitigate an influenza pandemic," Health Economics, John Wiley & Sons, Ltd., vol. 19(5), pages 518-531, May.
    14. Sun-Young Kim & Sue Goldie, 2008. "Cost-Effectiveness Analyses of Vaccination Programmes," PharmacoEconomics, Springer, vol. 26(3), pages 191-215, March.
    15. Benyun Shi & Guangliang Liu & Hongjun Qiu & Yu-Wang Chen & Shaoliang Peng, 2019. "Voluntary Vaccination through Perceiving Epidemic Severity in Social Networks," Complexity, Hindawi, vol. 2019, pages 1-13, February.
    16. Laurent Coudeville & Annelies Van Rie & Denis Getsios & J Jaime Caro & Pascal Crépey & Van Hung Nguyen, 2009. "Adult Vaccination Strategies for the Control of Pertussis in the United States: An Economic Evaluation Including the Dynamic Population Effects," PLOS ONE, Public Library of Science, vol. 4(7), pages 1-9, July.

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