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Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015–2017

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  • Lorenzo Cáceres Carrera
  • Carlos Victoria
  • Jose L Ramirez
  • Carmela Jackman
  • José E Calzada
  • Rolando Torres

Abstract

Background: Malaria is endemic in Darién and an assessment of the different factors affecting its epidemiology is crucial for the development of adequate strategies of surveillance, prevention, and disease control. The objective of this study was to determine the main characteristics of the epidemiological behavior of malaria in the Darien region. Methods: This research was comprised of a retrospective analysis to determine the incidence and malaria distribution in the Darien region from 2015 to 2017. We evaluated malaria indicators, disease distribution, incidence (by age group and sex), diagnostic methods, treatment, and control measures. In addition, we examined the cross-border migration activity and its possible contribution to the maintenance and distribution of malaria. Results: During the period of 2015–2017, we examined 41,141 thick blood smear samples, out of which 501 tested positive for malaria. Plasmodium vivax was responsible for 92.2% of those infections. Males comprised 62.7% of the total diagnosed cases. Meanwhile, a similar percentage, 62.7%, of the total cases were registered in economically active ages. The more frequent symptoms included fever (99.4%) and chills (97.4%), with 53.1% of cases registering between 2,000 and 6,000 parasites/μl of blood. The annual parasitic incidence (API) average was 3.0/1,000 inhabitants, while the slide positivity rate (SPR) was 1.2% and the annual blood examination rate (ABER) 22.5%. In Darién there is a constant internal and cross-border migration movement between Panama and Colombia. Malaria control measures consisted of the active and passive search of suspected cases and of the application of vector control measures. Conclusion: This study provides an additional perspective on malaria epidemiology in Darién. Additional efforts are required to intensify malaria surveillance and to achieve an effective control, eventually moving closer to the objective of malaria elimination. At the same time, there is a need for more eco-epidemiological, entomological and migratory studies to determine how these factors contribute to the patterns of maintenance and dissemination of malaria.

Suggested Citation

  • Lorenzo Cáceres Carrera & Carlos Victoria & Jose L Ramirez & Carmela Jackman & José E Calzada & Rolando Torres, 2019. "Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015–2017," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-30, November.
    • Handle: RePEc:plo:pone00:0224508
    DOI: 10.1371/journal.pone.0224508
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    1. José A Nájera & Matiana González-Silva & Pedro L Alonso, 2011. "Some Lessons for the Future from the Global Malaria Eradication Programme (1955–1969)," PLOS Medicine, Public Library of Science, vol. 8(1), pages 1-7, January.
    2. Peter W. Gething & David L. Smith & Anand P. Patil & Andrew J. Tatem & Robert W. Snow & Simon I. Hay, 2010. "Climate change and the global malaria recession," Nature, Nature, vol. 465(7296), pages 342-345, May.
    3. Simon I Hay & Carlos A Guerra & Peter W Gething & Anand P Patil & Andrew J Tatem & Abdisalan M Noor & Caroline W Kabaria & Bui H Manh & Iqbal R F Elyazar & Simon Brooker & David L Smith & Rana A Moyee, 2009. "A World Malaria Map: Plasmodium falciparum Endemicity in 2007," PLOS Medicine, Public Library of Science, vol. 6(3), pages 1-17, March.
    4. Sevilla-Casas, Elías, 1993. "Human mobility and malaria risk in the Naya river basin of Colombia," Social Science & Medicine, Elsevier, vol. 37(9), pages 1155-1167, November.
    5. Hannah C. Slater & Amanda Ross & André Lin Ouédraogo & Lisa J. White & Chea Nguon & Patrick G.T. Walker & Pengby Ngor & Ricardo Aguas & Sheetal P. Silal & Arjen M. Dondorp & Paul La Barre & Robert Bur, 2015. "Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies," Nature, Nature, vol. 528(7580), pages 94-101, December.
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