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Relationship between Working Hours and Power of Attention, Memory, Fatigue, Depression and Self-Efficacy One Year after Diagnosis of Clinically Isolated Syndrome and Relapsing Remitting Multiple Sclerosis

Author

Listed:
  • Peter Joseph Jongen
  • Keith Wesnes
  • Björn van Geel
  • Paul Pop
  • Evert Sanders
  • Hans Schrijver
  • Leo H Visser
  • H Jacobus Gilhuis
  • Ludovicus G Sinnige
  • Augustina M Brands
  • and the COGNISEC study group

Abstract

The role of cognitive domain dysfunction with respect to vocational changes in persons with Clinically Isolated Syndrome (CIS) and early Relapsing Remitting Multiple Sclerosis (eRRMS) is insufficiently known. We investigated thirty-three patients - 14 CIS, 19 eRRMS -, mean (standard deviation [SD]) time since diagnosis 13.5 (4.8) months and mean (SD) Expanded Disability Status Scale (EDSS) score 1.3 (1.1). Patients were assessed on the CDR System, a set of automated tests of cognitive function, which yielded scores for Power of Attention (ms), Continuity of Attention (#), Working Memory (SI), Episodic Memory (#) and Speed of Memory (ms). Work-related items and the confounding variables fatigue, depression, disease impact and self-efficacy, were assessed by self-report questionnaires. Patients had poorer Power of Attention compared to normative data (1187 [161.5] vs. 1070 [98.6]; P

Suggested Citation

  • Peter Joseph Jongen & Keith Wesnes & Björn van Geel & Paul Pop & Evert Sanders & Hans Schrijver & Leo H Visser & H Jacobus Gilhuis & Ludovicus G Sinnige & Augustina M Brands & and the COGNISEC study g, 2014. "Relationship between Working Hours and Power of Attention, Memory, Fatigue, Depression and Self-Efficacy One Year after Diagnosis of Clinically Isolated Syndrome and Relapsing Remitting Multiple Scler," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-7, May.
    • Handle: RePEc:plo:pone00:0096444
    DOI: 10.1371/journal.pone.0096444
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