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Optimal purchase of two-itemized drugs for a disease

Author

Listed:
  • C-H Lan

    (Nanhua University)

  • C-C Chen

    (Nanhua University)

Abstract

This paper submits a mathematical model called the two-itemized drugs purchasing decision (TDPD) model to conduct the optimal purchase of two-itemized drugs for healing a given disease. This TDPD model considers not only the annual estimated number of patients suffering from the given disease, the treatment courses, and the unit profit of each drug, but also the strength of the patient's perception on treatment quality, the different purchasing price of each drug with quantity discounts, the ordering cost, the holding cost, and other related costs to determine the optimal order quantity of each drug for achieving the maximum profit. A computerized solving program proposed in this paper applies tabu search technique as the main program and the all-units quantity discounts for economic order quantity as the sub-program to solve such a combinatorial problem, as well as perform sensitivity analyses on the changes by the strength of the patient's perception on treatment quality and the changes of annual estimated number of patients for the given disease. Two drugs, Lipitor and Gemnpid, to heal a disease ‘Hyperlipidaemia’ are considered as a case example in this study. This paper contributes a prototype quantitative method of purchasing decision for a given disease to a decision-maker with profound insights.

Suggested Citation

  • C-H Lan & C-C Chen, 2007. "Optimal purchase of two-itemized drugs for a disease," Journal of the Operational Research Society, Palgrave Macmillan;The OR Society, vol. 58(3), pages 309-316, March.
    • Handle: RePEc:pal:jorsoc:v:58:y:2007:i:3:d:10.1057_palgrave.jors.2602145
    DOI: 10.1057/palgrave.jors.2602145
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    References listed on IDEAS

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    1. N A Wassan & I H Osman, 2002. "Tabu search variants for the mix fleet vehicle routing problem," Journal of the Operational Research Society, Palgrave Macmillan;The OR Society, vol. 53(7), pages 768-782, July.
    2. Fred Glover, 1989. "Tabu Search---Part I," INFORMS Journal on Computing, INFORMS, vol. 1(3), pages 190-206, August.
    3. Fuchs, Victor R., 2000. "The future of health economics1," Journal of Health Economics, Elsevier, vol. 19(2), pages 141-157, March.
    4. Allen, Robin, 1992. "Policy implications of recent hospital competition studies," Journal of Health Economics, Elsevier, vol. 11(3), pages 347-351, October.
    5. de Ruyter, Ko & Bloemer, Jose & Peeters, Pascal, 1997. "Merging service quality and service satisfaction. An empirical test of an integrative model," Journal of Economic Psychology, Elsevier, vol. 18(4), pages 387-406, June.
    6. Propper, Carol, 1996. "Market structure and prices: The responses of hospitals in the UK National Health Service to competition," Journal of Public Economics, Elsevier, vol. 61(3), pages 307-335, September.
    7. Fred Glover, 1990. "Tabu Search—Part II," INFORMS Journal on Computing, INFORMS, vol. 2(1), pages 4-32, February.
    8. J-F Cordeau & G Laporte & A Mercier, 2001. "A unified tabu search heuristic for vehicle routing problems with time windows," Journal of the Operational Research Society, Palgrave Macmillan;The OR Society, vol. 52(8), pages 928-936, August.
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