c-Jun overexpression in CAR T cells induces exhaustion resistance
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DOI: 10.1038/s41586-019-1805-z
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- Carli M. Stewart & Elizabeth L. Siegler & R. Leo Sakemura & Michelle J. Cox & Truc Huynh & Brooke Kimball & Long Mai & Ismail Can & Claudia Manriquez Roman & Kun Yun & Olivia Sirpilla & James H. Girsc, 2024. "IL-4 drives exhaustion of CD8+ CART cells," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Anneke L. Eerkens & Koen Brummel & Annegé Vledder & Sterre T. Paijens & Marta Requesens & Dominik Loiero & Nienke Rooij & Annechien Plat & Floris-Jan Haan & Patty Klok & Refika Yigit & Thijs Roelofsen, 2024. "Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Eishiro Mizukoshi & Hidetoshi Nakagawa & Toshikatsu Tamai & Masaaki Kitahara & Kazumi Fushimi & Kouki Nio & Takeshi Terashima & Noriho Iida & Kuniaki Arai & Tatsuya Yamashita & Taro Yamashita & Yoshio, 2022. "Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8+ T cells," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
- Xiaofeng Liao & Wenxue Li & Hongyue Zhou & Barani Kumar Rajendran & Ao Li & Jingjing Ren & Yi Luan & David A. Calderwood & Benjamin Turk & Wenwen Tang & Yansheng Liu & Dianqing Wu, 2024. "The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Kwasi Adu-Berchie & Joshua M. Brockman & Yutong Liu & Tania W. To & David K. Y. Zhang & Alexander J. Najibi & Yoav Binenbaum & Alexander Stafford & Nikolaos Dimitrakakis & Miguel C. Sobral & Maxence O, 2023. "Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Bogang Wu & Xiaowen Zhang & Huai-Chin Chiang & Haihui Pan & Bin Yuan & Payal Mitra & Leilei Qi & Hayk Simonyan & Colin N. Young & Eric Yvon & Yanfen Hu & Nu Zhang & Rong Li, 2022. "RNA polymerase II pausing factor NELF in CD8+ T cells promotes antitumor immunity," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
- Shiyu Zuo & Chuo Li & Xiaolei Sun & Biping Deng & Yibing Zhang & Yajing Han & Zhuojun Ling & Jinlong Xu & Jiajia Duan & Zelin Wang & Xinjian Yu & Qinlong Zheng & Xiuwen Xu & Jiao Zong & Zhenglong Tian, 2024. "C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Veronika Bandara & Jade Foeng & Batjargal Gundsambuu & Todd S. Norton & Silvana Napoli & Dylan J. McPeake & Timona S. Tyllis & Elaheh Rohani-Rad & Caitlin Abbott & Stuart J. Mills & Lih Y. Tan & Emma , 2023. "Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Raymond Hall Yip Louie & Curtis Cai & Jerome Samir & Mandeep Singh & Ira W. Deveson & James M. Ferguson & Timothy G. Amos & Helen Marie McGuire & Kavitha Gowrishankar & Thiruni Adikari & Robert Balder, 2023. "CAR+ and CAR− T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
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