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Mimicking biological functionality with polymers for biomedical applications

Author

Listed:
  • Jordan J. Green

    (Translational Tissue Engineering Center, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine)

  • Jennifer H. Elisseeff

    (Translational Tissue Engineering Center, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine)

Abstract

The vast opportunities for biomaterials design and functionality enabled by mimicking nature continue to stretch the limits of imagination. As both biological understanding and engineering capabilities develop, more sophisticated biomedical materials can be synthesized that have multifaceted chemical, biological and physical characteristics designed to achieve specific therapeutic goals. Mimicry is being used in the design of polymers for biomedical applications that are required locally in tissues, systemically throughout the body, and at the interface with tissues.

Suggested Citation

  • Jordan J. Green & Jennifer H. Elisseeff, 2016. "Mimicking biological functionality with polymers for biomedical applications," Nature, Nature, vol. 540(7633), pages 386-394, December.
    • Handle: RePEc:nat:nature:v:540:y:2016:i:7633:d:10.1038_nature21005
    DOI: 10.1038/nature21005
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    Cited by:

    1. Xiaokang Zhang & Mengkui Cui & Shuoshuo Wang & Fei Han & Pingping Xu & Luyao Teng & Hang Zhao & Ping Wang & Guichu Yue & Yong Zhao & Guangfeng Liu & Ke Li & Jicong Zhang & Xiaoping Liang & Yingying Zh, 2022. "Extensible and self-recoverable proteinaceous materials derived from scallop byssal thread," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    2. Jiawei Sun & Sandra Kleuskens & Jiabin Luan & Danni Wang & Shaohua Zhang & Wei Li & Gizem Uysal & Daniela A. Wilson, 2023. "Morphogenesis of starfish polymersomes," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    3. Mei Zhu & Shengliang Wang & Zhenhui Li & Junbo Li & Zhijun Xu & Xiaoman Liu & Xin Huang, 2023. "Tyrosine residues initiated photopolymerization in living organisms," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    4. Yin Chen & Peng Gao & Lu Huang & Xing Tan & Ningling Zhou & Tong Yang & Hua Qiu & Xin Dai & Sean Michael & Qiufen Tu & Nan Huang & Zhihong Guo & Jianhua Zhou & Zhilu Yang & Hongkai Wu, 2021. "A tough nitric oxide-eluting hydrogel coating suppresses neointimal hyperplasia on vascular stent," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
    5. Yihong Zhong & Lijia Xu & Chen Yang & Le Xu & Guyu Wang & Yuna Guo & Songtao Cheng & Xiao Tian & Changjiang Wang & Ran Xie & Xiaojian Wang & Lin Ding & Huangxian Ju, 2023. "Site-selected in situ polymerization for living cell surface engineering," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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