IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v519y2015i7541d10.1038_nature14232.html
   My bibliography  Save this article

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

Author

Listed:
  • Benoit Chassaing

    (Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University)

  • Omry Koren

    (Faculty of Medicine, Bar Ilan University, Safed, 13115, Israel)

  • Julia K. Goodrich

    (Cornell University)

  • Angela C. Poole

    (Cornell University)

  • Shanthi Srinivasan

    (Emory University School of Medicine)

  • Ruth E. Ley

    (Cornell University)

  • Andrew T. Gewirtz

    (Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University)

Abstract

Emulsifying agents, which are common food additives in the human diet, induce low-grade inflammation and obesity/metabolic syndrome in mice, suggesting that further investigation into the potential impact of dietary emulsifiers on the gut microbiota and human heath are warranted.

Suggested Citation

  • Benoit Chassaing & Omry Koren & Julia K. Goodrich & Angela C. Poole & Shanthi Srinivasan & Ruth E. Ley & Andrew T. Gewirtz, 2015. "Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome," Nature, Nature, vol. 519(7541), pages 92-96, March.
    • Handle: RePEc:nat:nature:v:519:y:2015:i:7541:d:10.1038_nature14232
    DOI: 10.1038/nature14232
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature14232
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature14232?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Yadong Qi & Jiamin He & Yawen Zhang & Qiwei Ge & Qiwen Wang & Luyi Chen & Jilei Xu & Lan Wang & Xueqin Chen & Dingjiacheng Jia & Yifeng Lin & Chaochao Xu & Ying Zhang & Tongyao Hou & Jianmin Si & Shuj, 2023. "Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    2. Louzada, Maria Laura da Costa & Levy, Renata Bertazzi & Martins, Ana Paula Bortoletto & Claro, Rafael Moreira & Steele, Euridice Martinez & Verly Jr., Eliseu & Cafiero, Carlo & Monteiro, Carlos August, 2017. "Validating the usage of household food acquisition surveys to assess the consumption of ultra-processed foods: Evidence from Brazil," Food Policy, Elsevier, vol. 72(C), pages 112-120.
    3. Xiaotian Mao & Sabina Birgitte Larsen & Line Sidsel Fisker Zachariassen & Anders Brunse & Signe Adamberg & Josue Leonardo Castro Mejia & Frej Larsen & Kaarel Adamberg & Dennis Sandris Nielsen & Axel K, 2024. "Transfer of modified gut viromes improves symptoms associated with metabolic syndrome in obese male mice," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    4. Yun Han Kwon & Suhrid Banskota & Huaqing Wang & Laura Rossi & Jensine A. Grondin & Saad A. Syed & Yeganeh Yousefi & Jonathan D. Schertzer & Katherine M. Morrison & Michael G. Wade & Alison C. Holloway, 2022. "Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    5. Jianan Zhang & Morgan E. Walker & Katherine Z. Sanidad & Hongna Zhang & Yanshan Liang & Ermin Zhao & Katherine Chacon-Vargas & Vladimir Yeliseyev & Julie Parsonnet & Thomas D. Haggerty & Guangqiang Wa, 2022. "Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    6. Sandra M. Holmberg & Rachel H. Feeney & Vishnu Prasoodanan P.K. & Fabiola Puértolas-Balint & Dhirendra K. Singh & Supapit Wongkuna & Lotte Zandbergen & Hans Hauner & Beate Brandl & Anni I. Nieminen & , 2024. "The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    7. Emanuele Rinninella & Marco Cintoni & Pauline Raoul & Antonio Gasbarrini & Maria Cristina Mele, 2020. "Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track," IJERPH, MDPI, vol. 17(23), pages 1-15, November.
    8. Montserrat Costa-Font & Cesar Revoredo-Giha, 2019. "Introduction of New Food Products in China: Is There a Trend towards Healthier and Safer Products?," Social Sciences, MDPI, vol. 8(2), pages 1-23, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:519:y:2015:i:7541:d:10.1038_nature14232. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.