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The origins and the future of microfluidics

Author

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  • George M. Whitesides

    (Harvard University)

Abstract

The manipulation of fluids in channels with dimensions of tens of micrometres — microfluidics — has emerged as a distinct new field. Microfluidics has the potential to influence subject areas from chemical synthesis and biological analysis to optics and information technology. But the field is still at an early stage of development. Even as the basic science and technological demonstrations develop, other problems must be addressed: choosing and focusing on initial applications, and developing strategies to complete the cycle of development, including commercialization. The solutions to these problems will require imagination and ingenuity.

Suggested Citation

  • George M. Whitesides, 2006. "The origins and the future of microfluidics," Nature, Nature, vol. 442(7101), pages 368-373, July.
    • Handle: RePEc:nat:nature:v:442:y:2006:i:7101:d:10.1038_nature05058
    DOI: 10.1038/nature05058
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    Cited by:

    1. Saha, Sujit & Kundu, Balaram, 2023. "Multi-objective optimization of electrokinetic energy conversion efficiency and entropy generation for streaming potential driven electromagnetohydrodynamic flow of couple stress Casson fluid in micro," Energy, Elsevier, vol. 284(C).
    2. Mumuni Amadu & Adango Miadonye, 2024. "Interrelationship of Electric Double Layer Theory and Microfluidic Microbial Fuel Cells: A Review of Theoretical Foundations and Implications for Performance," Energies, MDPI, vol. 17(6), pages 1-31, March.
    3. Saroj Kumar & Lasse ten Siethoff & Malin Persson & Mercy Lard & Geertruy te Kronnie & Heiner Linke & Alf Månsson, 2012. "Antibodies Covalently Immobilized on Actin Filaments for Fast Myosin Driven Analyte Transport," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-16, October.
    4. Cairone, Fabiana & Mirabella, Daniela & Cabrales, Pedro J. & Intaglietta, Marcos & Bucolo, Maide, 2018. "Quantitative analysis of spatial irregularities in RBCs flows," Chaos, Solitons & Fractals, Elsevier, vol. 115(C), pages 349-355.
    5. Gaikwad, Harshad Sanjay & Basu, Dipankar Narayan & Mondal, Pranab Kumar, 2017. "Non-linear drag induced irreversibility minimization in a viscous dissipative flow through a micro-porous channel," Energy, Elsevier, vol. 119(C), pages 588-600.
    6. Brian S. Flowers & Ryan L. Hartman, 2012. "Particle Handling Techniques in Microchemical Processes," Challenges, MDPI, vol. 3(2), pages 1-18, August.
    7. Yang, Xu & Liang, Yingjie & Chen, Wen, 2019. "A fractal roughness model for the transport of fractional non-Newtonian fluid in microtubes," Chaos, Solitons & Fractals, Elsevier, vol. 126(C), pages 236-241.
    8. Yuqing Chang & Yuqian Wang & Wen Li & Zewen Wei & Shichuan Tang & Rui Chen, 2023. "Mechanisms, Techniques and Devices of Airborne Virus Detection: A Review," IJERPH, MDPI, vol. 20(8), pages 1-30, April.
    9. Yunhan Kim & Taekyum Kim & Byeng D. Youn & Sung-Hoon Ahn, 2022. "Machining quality monitoring (MQM) in laser-assisted micro-milling of glass using cutting force signals: an image-based deep transfer learning," Journal of Intelligent Manufacturing, Springer, vol. 33(6), pages 1813-1828, August.
    10. Hovav, Anat & Hemmert, Martin & Kim, Yoo Jung, 2011. "Determinants of Internet standards adoption: The case of South Korea," Research Policy, Elsevier, vol. 40(2), pages 253-262, March.
    11. Badriyah Alhalaili & Ileana Nicoleta Popescu & Carmen Otilia Rusanescu & Ruxandra Vidu, 2022. "Microfluidic Devices and Microfluidics-Integrated Electrochemical and Optical (Bio)Sensors for Pollution Analysis: A Review," Sustainability, MDPI, vol. 14(19), pages 1-38, October.
    12. Zain Hayat & Abdel El Abed, 2019. "Microfluidic Based Fast and Dynamic Droplet Interface Bilayer System (DIBS)," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 21(1), pages 15611-15619, September.
    13. Richard H. Steckel, 2008. "Biological Measures of the Standard of Living," Journal of Economic Perspectives, American Economic Association, vol. 22(1), pages 129-152, Winter.
    14. Banerjee, Rintu & Kumar, S.P. Jeevan & Mehendale, Ninad & Sevda, Surajbhan & Garlapati, Vijay Kumar, 2019. "Intervention of microfluidics in biofuel and bioenergy sectors: Technological considerations and future prospects," Renewable and Sustainable Energy Reviews, Elsevier, vol. 101(C), pages 548-558.
    15. Xuling Liu & Huafeng Song & Wensi Zuo & Guoyong Ye & Shaobo Jin & Liangwen Wang & Songjing Li, 2022. "Theoretical and Experimental Studies of a PDMS Pneumatic Microactuator for Microfluidic Systems," Energies, MDPI, vol. 15(22), pages 1-19, November.
    16. Rarotra, Saptak & Shahid, Shaik & De, Mahuya & Mandal, Tapas Kumar & Bandyopadhyay, Dipankar, 2021. "Graphite/RGO coated paper μ-electrolyzers for production and separation of hydrogen and oxygen," Energy, Elsevier, vol. 228(C).

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