IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v438y2005i7070d10.1038_nature04478.html
   My bibliography  Save this article

Angiogenesis in life, disease and medicine

Author

Listed:
  • Peter Carmeliet

    (Center of Transgene Technology and Gene Therapy, University of Leuven, Flanders Interuniversity Institute for Biotechnology (VIB))

Abstract

The growth of blood vessels (a process known as angiogenesis) is essential for organ growth and repair. An imbalance in this process contributes to numerous malignant, inflammatory, ischaemic, infectious and immune disorders. Recently, the first anti-angiogenic agents have been approved for the treatment of cancer and blindness. Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.

Suggested Citation

  • Peter Carmeliet, 2005. "Angiogenesis in life, disease and medicine," Nature, Nature, vol. 438(7070), pages 932-936, December.
    • Handle: RePEc:nat:nature:v:438:y:2005:i:7070:d:10.1038_nature04478
    DOI: 10.1038/nature04478
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature04478
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature04478?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Rocío Vega & Manuel Carretero & Rui D M Travasso & Luis L Bonilla, 2020. "Notch signaling and taxis mechanisms regulate early stage angiogenesis: A mathematical and computational model," PLOS Computational Biology, Public Library of Science, vol. 16(1), pages 1-31, January.
    2. Yuping Li & Mengzhuo Hou & Guangyu Lu & Natalia Ciccone & Xingdong Wang & Hengzhu Zhang, 2016. "The Prognosis of Anti-Angiogenesis Treatments Combined with Standard Therapy for Newly Diagnosed Glioblastoma: A Meta-Analysis of Randomized Controlled Trials," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-16, December.
    3. S. Kaessmeyer & H. Huenigen & S. Al Masri & P. Dieckhoefer & K. Richardson & J. Plendl, 2016. "Corpus luteal angiogenesis in a high milk production dairy breed differs from that of cattle with lower milk production levels," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 61(9), pages 497-503.
    4. Zélia Velez & Marco A. Campinho & Ângela R. Guerra & Laura García & Patricia Ramos & Olinda Guerreiro & Laura Felício & Fernando Schmitt & Maria Duarte, 2012. "Biological Characterization of Cynara cardunculus L. Methanolic Extracts: Antioxidant, Anti-proliferative, Anti-migratory and Anti-angiogenic Activities," Agriculture, MDPI, vol. 2(4), pages 1-21, December.
    5. Rui D M Travasso & Eugenia Corvera Poiré & Mario Castro & Juan Carlos Rodrguez-Manzaneque & A Hernández-Machado, 2011. "Tumor Angiogenesis and Vascular Patterning: A Mathematical Model," PLOS ONE, Public Library of Science, vol. 6(5), pages 1-10, May.
    6. Sadhukhan, Sounak & Mishra, P.K., 2022. "The notion of fractals in tumour angiogenic sprout initiation model based on cellular automata," Chaos, Solitons & Fractals, Elsevier, vol. 155(C).
    7. Atsuya Yaguchi & Mio Oshikawa & Go Watanabe & Hirotsugu Hiramatsu & Noriyuki Uchida & Chikako Hara & Naoko Kaneko & Kazunobu Sawamoto & Takahiro Muraoka & Itsuki Ajioka, 2021. "Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
    8. Moritz Gerstung & Hani Nakhoul & Niko Beerenwinkel, 2011. "Evolutionary Games with Affine Fitness Functions: Applications to Cancer," Dynamic Games and Applications, Springer, vol. 1(3), pages 370-385, September.
    9. Hanlin Lu & Peidong Yuan & Xiaoping Ma & Xiuxin Jiang & Shaozhuang Liu & Chang Ma & Sjaak Philipsen & Qunye Zhang & Jianmin Yang & Feng Xu & Cheng Zhang & Yun Zhang & Wencheng Zhang, 2023. "Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:438:y:2005:i:7070:d:10.1038_nature04478. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.